GRM1
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 3KS9,4OR2
Dynodwyr
Cyfenwau	GRM1, GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13, glutamate metabotropic receptor 1, SCA44
Dynodwyr allanol	OMIM:604473HomoloGene:649GeneCards:GRM1
PatrwmRNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •glutamate receptor activity •G protein-coupled receptor activity •signal transducer activity •GO:0001948, GO:0016582 protein binding •neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration •identical protein binding •G protein-coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration •G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential Cydrannau o'r gell •integral component of membrane •G protein-coupled receptor dimeric complex •GO:0097483, GO:0097481 postsynaptic density •bilen •G protein-coupled receptor homodimeric complex •cellbilen •integral component of plasma membrane •dendrite •neuron projection •cnewyllyn cell •presynaptic membrane •Schaffer collateral - CA1 synapse •glutamatergic synapse •postsynaptic density membrane Prosesau biolegol •cellular response to electrical stimulus •G protein-coupled glutamate receptor signaling pathway •positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway •regulation of MAPK cascade •regulation of sensory perception of pain •locomotory behavior •sensory perception of pain •GO:0072468 signal transduction •chemical synaptic transmission •regulation of synaptic transmission, glutamatergic •adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway •regulation of postsynaptic cytosolic calcium ion concentration •G protein-coupled receptor signaling pathway •regulation of postsynaptic membrane potential Sources:Amigo /QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2911	n/a
Ensembl	ENSG00000152822	n/a
UniProt	Q13255	n/a
RefSeq (mRNA)	NM_000838 NM_001114329 NM_001278064 NM_001278065 NM_001278066 NM_001278067	n/a
RefSeq (protein)	NP_001264993 NP_001264994 NP_001264995 NP_001264996	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynGRM1 ywGRM1 a elwir hefyd ynGlutamate metabotropic receptor 1 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q24.3.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GRM1.

• "Dominant Mutations in GRM1 Cause Spinocerebellar Ataxia Type 44.". Am J Hum Genet. 2017. PMID 28886343.
• "Age and gender effects of 11C-ITMM binding to metabotropic glutamate receptor type 1 in healthy human participants.". Neurobiol Aging. 2017. PMID 28431287.
• "Are Type 1 metabotropic glutamate receptors a viable therapeutic target for the treatment of cerebellar ataxia?". J Physiol. 2016. PMID 26748626.
• "Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells.". Biochem Pharmacol. 2015. PMID 26291396.
• "Metabotropic glutamate receptor 1 disrupts mammary acinar architecture and initiates malignant transformation of mammary epithelial cells.". Breast Cancer Res Treat. 2015. PMID 25859923.

• Genes on human chromosome
• Genynnau

• Erthyglau Bot Wici-Iechyd