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Neidio i'r cynnwys
Wicipedia
Chwilio

GABPA

Oddi ar Wicipedia
GABPA
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

1AWC,1SXD,2JUO

Dynodwyr
CyfenwauGABPA, E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07, GA binding protein transcription factor alpha subunit, GA binding protein transcription factor subunit alpha
Dynodwyr allanolOMIM:600609HomoloGene:1543GeneCards:GABPA
PatrwmRNA pattern
Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddDNA binding
sequence-specific DNA binding
GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity
GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001105 transcription coactivator activity
chromatin binding
GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001948, GO:0016582 protein binding
protein heterodimerization activity
GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Cydrannau o'r gellnucleoplasm
cnewyllyn cell
Prosesau biolegolcell differentiation
GO:0009373 regulation of transcription, DNA-templated
GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II
mitochondrion organization
in utero embryonic development
GO:1901227 negative regulation of transcription by RNA polymerase II
negative regulation of megakaryocyte differentiation
transcription, DNA-templated
GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II
transcription by RNA polymerase II
GO:1901313 positive regulation of gene expression
cellular response to dopamine
blastocyst formation
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

2551

n/a

Ensembl

ENSG00000154727

n/a

UniProt

Q06546
Q8IYS3

n/a

RefSeq (mRNA)

NM_001197297
NM_002040

n/a

RefSeq (protein)

NP_001184226
NP_002031
NP_002031.2

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynGABPA ywGABPA a elwir hefyd ynGA binding protein transcription factor, alpha subunit 60kDa a GA binding protein transcription factor alpha subunit (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 21, band 21q21.3.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GABPA.

  • NFT2
  • NRF2
  • NRF2A
  • E4TF1A
  • E4TF1-60
  • RCH04A07

Llyfryddiaeth

[golygu |golygu cod]
  • "GABPA predicts prognosis and inhibits metastasis of hepatocellular carcinoma.". BMC Cancer. 2017. PMID 28549418.
  • "Human Lineage-Specific Transcriptional Regulation through GA-Binding Protein Transcription Factor Alpha (GABPa).". Mol Biol Evol. 2016. PMID 26814189.
  • "Clinical characterisation of the CABP4-related retinal phenotype.". Br J Ophthalmol. 2013. PMID 23099293.
  • "The rs12594956 polymorphism in the NRF-2 gene is associated with top-level Spanish athlete's performance status.". J Sci Med Sport. 2013. PMID 22749526.
  • "An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study.". BMC Med Genet. 2011. PMID 21774808.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. GABPA - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=GABPA&oldid=4495481"
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