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Wicipedia
Chwilio

EPHA7

Oddi ar Wicipedia
EPHA7
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

2REI,3DKO,3H8M,3NRU

Dynodwyr
CyfenwauEPHA7, EHK-3, EHK3, EK11, HEK11, EPH receptor A7
Dynodwyr allanolOMIM:602190HomoloGene:20935GeneCards:EPHA7
PatrwmRNA pattern
Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddtransferase activity
nucleotide binding
protein kinase activity
GPI-linked ephrin receptor activity
ephrin receptor binding
kinase activity
GO:0001948, GO:0016582 protein binding
transmembrane receptor protein tyrosine kinase activity
protein tyrosine kinase activity
ATP binding
axon guidance receptor activity
ephrin receptor activity
chemorepellent activity
receptor tyrosine kinase
transmembrane signaling receptor activity
transmembrane-ephrin receptor activity
Cydrannau o'r gellintegral component of membrane
postsynaptic membrane
bilen
neuromuscular junction
Cellbilen
integral component of plasma membrane
soma
dendrite
Schaffer collateral - CA1 synapse
hippocampal mossy fiber to CA3 synapse
glutamatergic synapse
integral component of postsynaptic specialization membrane
integral component of postsynaptic density membrane
cytoplasm
neuron projection
receptor complex
Prosesau biolegolGO:0097285 apoptotic process
positive regulation of protein phosphorylation
regulation of protein autophosphorylation
phosphorylation
transmembrane receptor protein tyrosine kinase signaling pathway
ephrin receptor signaling pathway
negative regulation of synapse assembly
regulation of cysteine-type endopeptidase activity involved in apoptotic process
nervous system development
branching morphogenesis of a nerve
multicellular organism development
protein phosphorylation
negative regulation of collateral sprouting
positive regulation of neuron apoptotic process
brain development
nephric duct morphogenesis
regulation of cell-cell adhesion
regulation of ERK1 and ERK2 cascade
positive regulation of apoptotic process
peptidyl-tyrosine phosphorylation
regulation of peptidyl-tyrosine phosphorylation
retinal ganglion cell axon guidance
negative chemotaxis
regulation of postsynapse organization
negative regulation of signal transduction
cell differentiation
negative regulation of apoptotic process
positive regulation of ERK1 and ERK2 cascade
axon guidance
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

2045

n/a

Ensembl

ENSG00000135333

n/a

UniProt

Q15375

n/a

RefSeq (mRNA)

NM_001288629
NM_001288630
NM_004440

n/a

RefSeq (protein)
NP_001275558
NP_001275559
NP_004431
NP_001363394
NP_001363395

NP_001363396
NP_001363397
NP_001363398
NP_001363399
NP_001363400

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynEPHA7 ywEPHA7 a elwir hefyd ynEPH receptor A7 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6q16.1.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EPHA7.

  • EHK3
  • EK11
  • EHK-3
  • HEK11

Llyfryddiaeth

[golygu |golygu cod]
  • "Knockdown of ephrin receptor A7 suppresses the proliferation and metastasis of A549 human lung cancer cells.". Mol Med Rep. 2016. PMID 26936314.
  • "Effect of EphA7 Silencing on Proliferation, Invasion and Apoptosis in Human Laryngeal Cancer Cell Lines Hep-2 and AMC-HN-8.". Cell Physiol Biochem. 2015. PMID 25968442.
  • "[Expression of EphA7 protein in primary hepatocellular carcinoma and its clinical significance].". Zhonghua Wai Ke Za Zhi. 2010. PMID 20302756.
  • "Secreted form of EphA7 in lung cancer.". Int J Oncol. 2010. PMID 20126984.
  • "Aberrant methylation of EphA7 in human prostate cancer and its relation to clinicopathologic features.". Int J Cancer. 2009. PMID 18821581.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. EPHA7 - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=EPHA7&oldid=4495288"
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