EGR1
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 4R2A,4R2C,4R2D,4X9J
Dynodwyr
Cyfenwau	EGR1, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268, ZNF225, early growth response 1
Dynodwyr allanol	OMIM:128990HomoloGene:56394GeneCards:EGR1
PatrwmRNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •DNA binding •sequence-specific DNA binding •RNA polymerase II transcription regulatory region sequence-specific DNA binding •GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity •GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific •GO:0000975 transcription cis-regulatory region binding •metal ion binding •transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding •GO:0001948, GO:0016582 protein binding •histone acetyltransferase binding •nucleic acid binding •hemi-methylated DNA-binding •double-stranded methylated DNA binding •zinc ion binding •promoter-specific chromatin binding •GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell •nucleoplasm •cnewyllyn cell •cytoplasm Prosesau biolegol •regulation of apoptotic process •cellular response to organic substance •GO:0009373 regulation of transcription, DNA-templated •glomerular mesangial cell proliferation •GO:1901227 negative regulation of transcription by RNA polymerase II •response to glucose •transcription by RNA polymerase II •BMP signaling pathway •transcription, DNA-templated •GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated •response to insulin •interleukin-1-mediated signaling pathway •cellular response to mycophenolic acid •T cell differentiation •type I interferon signaling pathway •positive regulation of glomerular metanephric mesangial cell proliferation •cellular response to gamma radiation •regulation of transcription from RNA polymerase II promoter in response to hypoxia •skeletal muscle cell differentiation •cellular response to heparin •regulation of protein sumoylation •negative regulation of canonical Wnt signaling pathway •GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II •cellular response to interleukin-8 •response to hypoxia •response to ischemia •estrous cycle •positive regulation of hormone biosynthetic process •regulation of progesterone biosynthetic process •GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II •GO:1901313 positive regulation of gene expression •circadian regulation of gene expression •locomotor rhythm •proses rythmig •circadian temperature homeostasis •positive regulation of neuron death •positive regulation of tau-protein kinase activity Sources:Amigo /QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1958	n/a
Ensembl	ENSG00000120738	n/a
UniProt	P18146	n/a
RefSeq (mRNA)	NM_001964	n/a
RefSeq (protein)	NP_001955	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynEGR1 ywEGR1 a elwir hefyd ynEarly growth response 1 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q31.2.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EGR1.

• "Thermodynamic Additivity for Impacts of Base-Pair Substitutions on Association of the Egr-1 Zinc-Finger Protein with DNA.". Biochemistry. 2016. PMID 27933778.
• "Increased Expression of EGR-1 in Diabetic Human Adipose Tissue-Derived Mesenchymal Stem Cells Reduces Their Wound Healing Capacity.". Stem Cells Dev. 2016. PMID 26988763.
• "EGR1 controls divergent cellular responses of distinctive nucleus pulposus cell types.". BMC Musculoskelet Disord. 2016. PMID 26975996.
• "Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts.". J Formos Med Assoc. 2017. PMID 26922429.
• "Egr-1 identifies neointimal remodeling and relates to progression in human pulmonary arterial hypertension.". J Heart Lung Transplant. 2016. PMID 26774383.

• Genes on human chromosome
• Genynnau

• Erthyglau Bot Wici-Iechyd