CYP17A1
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 3RUK,3SWZ,4NKV,4NKW,4NKX,4NKY,4NKZ
Dynodwyr
Cyfenwau	CYP17A1, CPT7, CYP17, P450C17, S17AH, cytochrome P450 family 17 subfamily A member 1
Dynodwyr allanol	OMIM:609300HomoloGene:73875GeneCards:CYP17A1
EC number	1.14.14.32 1.14.14.19, 1.14.14.32
PatrwmRNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •iron ion binding •oxygen binding •metal ion binding •steroid 17-alpha-monooxygenase activity •monooxygenase activity •heme binding •GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen •lyase activity •oxidoreductase activity •17-alpha-hydroxyprogesterone aldolase activity Cydrannau o'r gell •endoplasmic reticulum membrane •bilen •axon •soma •Reticwlwm endoplasmig Prosesau biolegol •progesterone metabolic process •androgen biosynthetic process •glucocorticoid biosynthetic process •sterol metabolic process •hormone biosynthetic process •steroid biosynthetic process •steroid metabolic process •sex differentiation Sources:Amigo /QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1586	n/a
Ensembl	ENSG00000148795	n/a
UniProt	P05093	n/a
RefSeq (mRNA)	NM_000102	n/a
RefSeq (protein)	NP_000093	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynCYP17A1 ywCYP17A1 a elwir hefyd ynCytochrome P450 family 17 subfamily A member 1 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 10, band 10q24.32.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYP17A1.

• "Cytochrome b5 Activates the 17,20-Lyase Activity of Human Cytochrome P450 17A1 by Increasing the Coupling of NADPH Consumption to Androgen Production.". Biochemistry. 2016. PMID 27426448.
• "Common Genetic Variation in CYP17A1 and Response to Abiraterone Acetate in Patients with Metastatic Castration-Resistant Prostate Cancer.". Int J Mol Sci. 2016. PMID 27409606.
• "Specificity of anti-prostate cancer CYP17A1 inhibitors on androgen biosynthesis.". Biochem Biophys Res Commun. 2016. PMID 27395338.
• "Mechanism of 17α,20-Lyase and New Hydroxylation Reactions of Human Cytochrome P450 17A1: 18O LABELING AND OXYGEN SURROGATE EVIDENCE FOR A ROLE OF A PERFERRYL OXYGEN.". J Biol Chem. 2016. PMID 27339894.
• "Clinical and molecular manifestation of fifteen 17OHD patients: a novel mutation and a founder effect.". Endocrine. 2016. PMID 27150612.

• Genes on human chromosome
• Genynnau

• Erthyglau Bot Wici-Iechyd