CSF2
Strwythurau PDB Human UniProt search:PDBeRCSB Rhestr o ddynodwyr PDB 1CSG,2GMF,4NKQ,5C7X,5D70,5D71,5D72,4RS1
Dynodwyr
Cyfenwau	CSF2, GMCSF, colony stimulating factor 2, CSF
Dynodwyr allanol	OMIM:138960HomoloGene:600GeneCards:CSF2
PatrwmRNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd •growth factor activity •granulocyte macrophage colony-stimulating factor receptor binding •GO:0001948, GO:0016582 protein binding •protein tyrosine kinase activity •cytokine activity Cydrannau o'r gell •extracellular region •intracellular membrane-bounded organelle •extracellular space Prosesau biolegol •negative regulation of cytolysis •positive regulation of macrophage derived foam cell differentiation •regulation of cell population proliferation •MAPK cascade •positive regulation of podosome assembly •negative regulation of extrinsic apoptotic signaling pathway in absence of ligand •positive regulation of interleukin-23 production •GO:1901313 positive regulation of gene expression •embryonic placenta development •epithelial fluid transport •regulation of gene expression •dendritic cell differentiation •myeloid dendritic cell differentiation •macrophage activation •cellular response to lipopolysaccharide •GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response •monocyte differentiation •response to fluid shear stress •response to silicon dioxide •neutrophil differentiation •peptidyl-tyrosine phosphorylation •regulation of circadian sleep/wake cycle, sleep •histamine secretion •positive regulation of tyrosine phosphorylation of STAT protein •cellular response to granulocyte macrophage colony-stimulating factor stimulus •regulation of myeloid cell differentiation •regulation of signaling receptor activity •GO:0045996 negative regulation of transcription, DNA-templated •cytokine-mediated signaling pathway •positive regulation of cell population proliferation •macrophage differentiation Sources:Amigo /QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1437	n/a
Ensembl	ENSG00000164400	n/a
UniProt	P04141	n/a
RefSeq (mRNA)	NM_000758	n/a
RefSeq (protein)	NP_000749	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynCSF2 ywCSF2 a elwir hefyd ynColony stimulating factor 2 (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q31.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CSF2.

• CSF
• GMCSF

• "Honokiol possesses potential anti-inflammatory effects on rheumatoid arthritis and GM-CSF can be a target for its treatment.". Int J Clin Exp Pathol. 2015. PMID 26339358.
• "T cell expression of granulocyte-macrophage colony-stimulating factor in juvenile arthritis is contingent upon Th17 plasticity.". Arthritis Rheumatol. 2014. PMID 24692225.
• "Pichia pastoris versus Saccharomyces cerevisiae: a case study on the recombinant production of human granulocyte-macrophage colony-stimulating factor.". BMC Res Notes. 2017. PMID 28376863.
• "Stimulatory versus suppressive effects of GM-CSF on tumor progression in multiple cancer types.". Exp Mol Med. 2016. PMID 27364892.
• "Granulocyte macrophage colony-stimulating factor predicts postoperative recurrence of clear-cell renal cell carcinoma.". Oncotarget. 2016. PMID 27016418.

• Genes on human chromosome
• Genynnau

• Erthyglau Bot Wici-Iechyd