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Wicipedia
Chwilio

CD1D

Oddi ar Wicipedia
CD1D
Strwythurau
PDBHuman UniProt search:PDBeRCSB
Rhestr o ddynodwyr PDB

4WO4,1ZT4,2PO6,3HUJ,3SDX,3TZV,3U0P,3VWJ,3VWK,4EN3,4LHU,4MNG,4MQ7,4WW2

Dynodwyr
CyfenwauCD1D, CD1A, R3, R3G1, CD1d molecule
Dynodwyr allanolOMIM:188410HomoloGene:1337GeneCards:CD1D
PatrwmRNA pattern
Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaiddbeta-2-microglobulin binding
lipopeptide binding
GO:0031493 histone binding
endogenous lipid antigen binding
lipid antigen binding
exogenous lipid antigen binding
cell adhesion molecule binding
GO:0001948, GO:0016582 protein binding
Cydrannau o'r gellcytoplasm
integral component of membrane
endosome
endoplasmic reticulum membrane
bilen
integral component of plasma membrane
cell surface
lysosomal membrane
basolateral plasma membrane
lysosome
endosome membrane
Cellbilen
Reticwlwm endoplasmig
extracellular space
external side of plasma membrane
Prosesau biolegolimmune system process
T cell selection
heterotypic cell-cell adhesion
positive regulation of T cell proliferation
detection of bacterium
positive regulation of innate immune response
antigen processing and presentation, exogenous lipid antigen via MHC class Ib
innate immune response
GO:0022415 viral process
antigen processing and presentation, endogenous lipid antigen via MHC class Ib
regulation of immune response
positive regulation of T cell mediated cytotoxicity
GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response
Sources:Amigo /QuickGO
Orthologau
SpeciesBod dynolLlygoden
Entrez

912

n/a

Ensembl

ENSG00000158473

n/a

UniProt

P15813

n/a

RefSeq (mRNA)

NM_001766
NM_001319145
NM_001371761
NM_001371762
NM_001371763

n/a

RefSeq (protein)

NP_001306074
NP_001757
NP_001358690
NP_001358691
NP_001358692

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn ycorff dynol gan y genynCD1D ywCD1D a elwir hefyd ynCD1d molecule (Saesneg). Segment oDNA yw'rgenyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.1.[2]

Cyfystyron

[golygu |golygu cod]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD1D.

  • R3
  • CD1A
  • R3G1

Llyfryddiaeth

[golygu |golygu cod]
  • "CD1d is a novel cell-surface marker for human monocytic myeloid-derived suppressor cells with T cell suppression activity in peripheral blood after allogeneic hematopoietic stem cell transplantation.". Biochem Biophys Res Commun. 2018. PMID 29108995.
  • "Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease.". J Infect Dis. 2016. PMID 27368347.
  • "The tumor antigen N-glycolyl-GM3 is a human CD1d ligand capable of mediating B cell and natural killer T cell interaction.". Cancer Immunol Immunother. 2016. PMID 26969612.
  • "The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells.". Proc Natl Acad Sci U S A. 2016. PMID 26798067.
  • "Increased Expression of Two Alternative Spliced Variants of CD1d Molecule in Human Gastric Cancer.". Iran J Immunol. 2015. PMID 26119195.

Cyfeiriadau

[golygu |golygu cod]
  1. "Human PubMed Reference:".
  2. CD1D - Cronfa NCBI
Wedi dod o "https://cy.wikipedia.org/w/index.php?title=CD1D&oldid=4742826"
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