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PLOS is a non-profit organization on a mission to drive open science forward with measurable, meaningful change in research publishing, policy, and practice.

Building on a strong legacy of pioneering innovation, PLOS continues to be a catalyst, reimagining models to meet open science principles, removing barriers and promoting inclusion in knowledge creation and sharing, and publishing research outputs that enable everyone to learn from, reuse and build upon scientific knowledge.

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Curiosity is limitless. Discover more research that fascinates you with expertly curated, topic-specific PLOS Collections. Everything we publish is always Open Access so there are no restrictions on how you search, read, share, and reuse collections to inspire your future discoveries.

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  • Biology & Life SciencesA PLOS Collection’Omics of Cellular Signaling Pathways
    Published June 4, 2020Curated Collections

    The Signaling Pathways Project is a multi-omics knowledgebase based upon public, manually curated transcriptomic and cistromic (ChIP-Seq) datasets involving genetic and small molecule manipulations of…

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  • Medicine & HealthA PLOS CollectionBacterial Antimicrobial Resistance: Surveillance and Prevention
    Published July 12, 2023Special Issues
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  • Medicine & HealthA PLOS CollectionCOVID-19 Pandemic and Global Mental Health
    Published April 3, 2023Special Issues

    In this PLOS Medicine Special Issue, we present a fascinating array of research papers which provide insights into various facets of mental health during the pandemic. Key themes include increases in…

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  • Medicine & HealthA PLOS CollectionGlobal Child Health: From Birth to Adolescence and Beyond
    Published September 28, 2021Special Issues

    In 2000, the UN adopted the Millennium Development Goals (MDGs), which were intended to address key determinants of human health and welfare, including poverty, hunger, and disease. One of the MDGs…

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  • Medicine & HealthA PLOS CollectionTrafficking, Exploitation and Health
    Published September 23, 2020Partnered Collections, Special Issues

    The health consequences of human trafficking and exploitation are sufficiently prevalent and damaging that they comprise a public health problem of global magnitude. This PLOS Collection offers…

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  • Medicine & HealthA PLOS CollectionRegulatory Harmonization Collection
    Published August 12, 2020Partnered Collections, Special Issues

    While regulation of medicines is a key pillar of any health system assuring access to quality medicines, an unoptimized regulatory system is a barrier to access. Over the last 8 years the East African…

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  • Medicine & HealthA PLOS CollectionAdvances in Clinical Trial Design for Development of New Treatments for Tuberculosis
    Published June 30, 2020Partnered Collections, Special Issues

    With recent opportunities to test combinations of new and repurposed drugs for the treatment of TB, new questions arise for optimal clinical trial design. To address these, in March 2018 WHO organized…

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  • Medicine & HealthA PLOS CollectionHigh-Quality Health Systems
    Published April 7, 2020Partnered Collections, Special Issues

    High quality health care will be critical to attaining the Sustainable Development Goals in low- and middle income countries. However, little is known on levels of quality and its distribution within…

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  • collectionA PLOS CollectionRefugee and Migrant Health
    Published April 2, 2020Special Issues

    At the 72nd World Health Assembly held during May 20–28 of this year in Geneva, Switzerland, a very welcome global action plan was agreed which seeks to establish a “framework of…

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  • collectionA PLOS CollectionSubstance Use, Misuse, and Dependence: Prevention and Treatment
    Published April 1, 2020Special Issues

    Substance use and misuse affect people worldwide, of all ages and from all walks of life, resulting in a substantial burden of ill health and mortality, and presenting big challenges in prevention and…

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  • Medicine & HealthA PLOS CollectionMachine Learning in Health and Biomedicine
    Published August 21, 2019Special Issues

    Modern statistical modeling techniques—often called machine learning—are posited as a transformative force for human health. High-profile reports of diagnostic success demonstrate…

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