While the player does not have a Black Kyurem or White Kyurem, the DNA Splicers can be used to fuse Kyurem with Reshiram or Zekrom to become White Kyurem or Black Kyurem, respectively.
While the player has a Black Kyurem or White Kyurem, the DNA Splicers can be used to separate White Kyurem or Black Kyurem into Kyurem and the original Reshiram or Zekrom. All properties of the Reshiram or Zekrom will be retained.
The DNA Splicers can only fuse together one Kyurem and Reshiram or Zekrom at a time. In order to fuse a Kyurem with a different Reshiram or Zekrom, any existing fusion must be undone.
The DNA Splicers first appeared inThe Frozen World, where they were revealed to be inDrayden's possession. In order to obtain the item for their plans,Team Plasma attackedOpelucid City whileColress used thePlasma Frigate to freeze the entire city, allowingZinzolin to steal the DNA Splicers from Drayden.
The DNA Splicers first appeared inAbyssal Ruins, whereBlake revealed that he had possessed them ever since he was a little child, not knowing how he got them. AfterColress managed to makeZinzolin spill out his information regardingKyurem's Absofusion, he relayed this information toGhetsis, who had Kyurem call out to the DNA Splicers, causing them and Blake, who was trying to hold on to them, to fly up towards Kyurem. The item's energy eventually repelled Blake from it, and once Ghetsis ordered Kyurem to absorbN'sZekrom, Kyurem absorbed the DNA Splicers and forced Zekrom to turn into theDark Stone, which it used to transform itself into Black Kyurem.