PMP-22apoptozno srodni efektor p53 jestplazmamembranski protein koji je kodljudi kodiran genom PERP .[ 5] [ 6]
Dužinapolipeptidnog lanca je 193aminokiseline , аmolekulska težina 21.386Da .[ 7]
10 20 30 40 50 MIRCGLACER CRWILPLLLL SAIAFDIIAL AGRGWLQSSD HGQTSSLWWK CSQEGGGSGS YEEGCQSLME YAWGRAAAAM LFCGFIILVI CFILSFFALC GPQMLVFLRV IGGLLALAAV FQIISLVIYP VKYTQTFTLH ANPAVTYIYN WAYGFGWAAT IILIGCAFFF CCLPNYEDDL LGNAKPRYFY TSA
PERP je direktnatranskripcijska metap53 , ali se njegova transkripcija može regulirati i drugimfaktorima transkripcije .[ 8]
PERP je važan za razvojkože , a gubitak PERP-a povezan je s razvojem i progresijom nekoliko tipova ljudskihkancera .[ 8]
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