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Featured Review - Harnessing ferroptosis for precision oncology: challenges and prospects
Fernández-Acosta, VandenBerghe and colleagues review how clinical integration of ferroptosis-driven treatments in cancer care can be faciliated by machine learning-based analysis of molecular tumor profiling
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Small RNA structure and regulation
Genome organization and evolution
Structure, function, and regulation of membrane transport proteins
Human microbiome in health and disease
Ion channels and channelopathies
Mitochondrial metabolism and dynamics
Organoids: advancements in normal development and disease modeling, and regenerative medicine
Immunosenescence
Vasculogenesis and angiogenesis in vivo and in vitro
Aging microenvironment and disease
Integrative and translational serial dependence
Synaptic plasticity, learning, and memory
Evolution of immunity
Conservation genomics
Phase separation in homeostasis and disease
Lipid metabolism in physiology and cell function
Computational inference of protein conformations and interactions
Stem cells and cancer
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Articles
Single-cell transcriptomic dynamics of scallop heart reveals the heterogeneous response to heat stress
Authors:Danyang Wang, Na Liu, Xiangfu Kong, Xinghai Zhu, Yangfan Wang, Jingjie Hu and Zhenmin Bao
Content type:Research15 April 2025A self-limiting sterile insect technique alternative forCeratitis capitata
Authors:Serafima Davydova, Junru Liu, Yiran Liu, Kavya Prince, Jonathan Mann, Nikolay P. Kandul, W. Evan Braswell, Jackson Champer, Omar S. Akbari and Angela Meccariello
Content type:Research12 April 2025Dysregulated lipid metabolism in a retinal pigment epithelial cell model and serum of patients with age-related macular degeneration
Authors:Ana Álvarez-Barrios, Lydia Álvarez, Pilar Sáenz de Santa María, Montserrat García, Jorge R. Álvarez-Buylla, Rosario Pereiro and Héctor González-Iglesias
Content type:Research12 April 2025Dynamic substrate topographies drive actin- and vimentin-mediated nuclear mechanoprotection events in human fibroblasts
Authors:Maaike Bril, Jules N. Boesveld, Leila S. Coelho-Rato, Cecilia M. Sahlgren, Carlijn V. C. Bouten and Nicholas A. Kurniawan
Content type:Research7 April 2025Formant analysis of vertebrate vocalizations: achievements, pitfalls, and promises
Authors:W. Tecumseh Fitch, Andrey Anikin, Katarzyna Pisanski, Daria Valente and David Reby
Content type:Review7 April 2025
Research
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans
Marco Sazzini et al.
Published on: 22 May 2020
Research
Wonky whales: the evolution of cranial asymmetry in cetaceans
Ellen Coombset al.
Published on: 10 July 2020
Research
Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants
Zhichao Xu et al.
Published on: 18 June 2020
Research
Relationship between oxygen consumption and neuronal activity in a defined neural circuit
Suzan Özugur et al.
Published on: 03 July 2020
Review
X-ray computed tomography in life sciences
Shelley D. Rawsonet al.
Published 27 February 2020
Comment
The merger that made us
Buzz Baum and David Baum
Published 24 June 2020
Review
Protein assembly systems in natural and synthetic biology
Giulio Chiesaet al.
Published: 26 March 2020
Comment
Improving the usability and comprehensiveness of microbial databases
Caitlin Loeffler et al.
Published: 07 April 2020
scribblemutants promote aPKC and JNK-dependent epithelial neoplasia independently of Crumbs
Authors:Gregory R Leong, Karen R Goulding, Nancy Amin, Helena E Richardson and Anthony M Brumby
Content type:Research article24 September 2009Molecular dynamics simulations and drug discovery
Authors:Jacob D Durrant and J Andrew McCammon
Content type:Review28 October 2011Structure and function of mitochondrial membrane protein complexes
Authors:Werner Kühlbrandt
Content type:Review29 October 2015Q&A: What is a pathogen? A question that begs the point
Authors:Liise-anne Pirofski and Arturo Casadevall
Content type:Question and Answer31 January 2012Q&A: What are exosomes, exactly?
Authors:James R. Edgar
Content type:Question and Answer13 June 2016
Focus: Plant Pathogens
The broad use of the Pm8 resistance gene in wheat resulted in hypermutation of the AvrPm8 gene in the powdery mildew pathogen
Lukas Kunz et al.
Published inBMC Biology8 February 2023
Combined pangenomics and transcriptomics reveals core and redundant virulence processes in a rapidly evolving fungal plant pathogen
Hongxin Chen et al.
Published inBMC Biology 6 February 2023
The extrachromosomal circular DNAs of the rice blast pathogen Magnaporthe oryzae contain a wide variety of LTR retrotransposons, genes, and effectors
Pierre M. Joubert & Ksenia V. Krasileva
Published inBMC Biology 23 November 2022
The Venturia inaequalis effector repertoire is dominated by expanded families with predicted structural similarity, but unrelated sequence, to avirulence proteins from other plant-pathogenic fungi
Mercedes Rocafortet al.
Published inBMC Biology 3 November 2022
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Research Communities: Behind the Paper
We are now collaborating withResearch Communities, allowing authors to share experiences designing the study and collecting data by writing their own blog-style post on the paper.
Read the latestBehind the Paper articles here:
Cones, sticks and croissants: Early cephalopod evolution
Alexander Pohle
Published Apr 14 2022
Tentacular team up: Deep partnerships between sea anemones and bacteria
Shana Goffredi
Published Jan 18 2021
Who's a Bonehead? Novel Insights into Evolutionary History from Reptilian Skull Roof Structure
Roy Ebel
Published Nov 30 2020
Digging into the past of olive trees
Toni Gabaldón
Published Oct 26 2020
