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glmSparseNet

This is thereleased version of glmSparseNet; for the devel version, seeglmSparseNet.

Network Centrality Metrics for Elastic-Net Regularized Models

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DOI: 10.18129/B9.bioc.glmSparseNet


Bioconductor version: Release (3.22)

glmSparseNet is an R-package that generalizes sparse regression models when the features (e.g. genes) have a graph structure (e.g. protein-protein interactions), by including network-based regularizers. glmSparseNet uses the glmnet R-package, by including centrality measures of the network as penalty weights in the regularization. The current version implements regularization based on node degree, i.e. the strength and/or number of its associated edges, either by promoting hubs in the solution or orphan genes in the solution. All the glmnet distribution families are supported, namely "gaussian", "poisson", "binomial", "multinomial", "cox", and "mgaussian".

Author: André Veríssimo [aut, cre]ORCID iD ORCID: 0000-0002-2212-339X, Susana Vinga [aut], Eunice Carrasquinha [ctb], Marta Lopes [ctb]

Maintainer: André Veríssimo <andre.verissimo at tecnico.ulisboa.pt>

Citation (from within R, entercitation("glmSparseNet")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("glmSparseNet")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

To view documentation for the version of this package installed in your system, start R and enter:

browseVignettes("glmSparseNet")
Breast survival dataset using network from STRING DBHTMLR Script
Example for Classification -- Breast Invasive CarcinomaHTMLR Script
Example for Survival Data -- Breast Invasive CarcinomaHTMLR Script
Example for Survival Data -- Prostate AdenocarcinomaHTMLR Script
Example for Survival Data -- Skin MelanomaHTMLR Script
Separate 2 groups in Cox regressionHTMLR Script
Reference ManualPDF
NEWSText

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsClassification,DimensionReduction,GraphAndNetwork,Network,Regression,Software,StatisticalMethod,Survival
Version1.28.0
In Bioconductor sinceBioC 3.8 (R-3.5) (7 years)
LicenseGPL-3
DependsR (>= 4.3.0)
ImportsbiomaRt,checkmate,dplyr,forcats,futile.logger,ggplot2,glue,httr,lifecycle, methods, parallel,readr,rlang,glmnet,Matrix,MultiAssayExperiment,SummarizedExperiment,survminer,TCGAutils, utils
System Requirements
URLhttps://www.github.com/sysbiomed/glmSparseNet
Bug Reportshttps://www.github.com/sysbiomed/glmSparseNet/issues
See More
SuggestsBiocStyle,curatedTCGAData,knitr,magrittr,reshape2,pROC,rmarkdown,survival,testthat,VennDiagram,withr
Linking To
Enhances
Depends On Me
Imports Mepriorityelasticnet
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source PackageglmSparseNet_1.28.0.tar.gz
Windows Binary (x86_64) glmSparseNet_1.28.0.zip
macOS Binary (x86_64)glmSparseNet_1.28.0.tgz
macOS Binary (arm64)glmSparseNet_1.28.0.tgz
Source Repositorygit clone https://git.bioconductor.org/packages/glmSparseNet
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/glmSparseNet
Bioc Package Browserhttps://code.bioconductor.org/browse/glmSparseNet/
Package Short Urlhttps://bioconductor.org/packages/glmSparseNet/
Package Downloads ReportDownload Stats

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