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XNAString

This package isdeprecated. It will probably be removed from Bioconductor. Please refer to the package end-of-life guidelines for more information.

This package is for version 3.22 of Bioconductor.This package has been removed from Bioconductor.For the last stable, up-to-date release version, seeXNAString.

Efficient Manipulation of Modified Oligonucleotide Sequences

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DOI: 10.18129/B9.bioc.XNAString


Bioconductor version: Release (3.22)

The XNAString package allows for description of base sequences and associated chemical modifications in a single object. XNAString is able to capture single stranded, as well as double stranded molecules. Chemical modifications are represented as independent strings associated with different features of the molecules (base sequence, sugar sequence, backbone sequence, modifications) and can be read or written to a HELM notation. It also enables secondary structure prediction using RNAfold from ViennaRNA. XNAString is designed to be efficient representation of nucleic-acid based therapeutics, therefore it stores information about target sequences and provides interface for matching and alignment functions from Biostrings and pwalign packages.

Author: Anna Górska [aut], Marianna Plucinska [aut, cre], Lykke Pedersen [aut], Lukasz Kielpinski [aut], Disa Tehler [aut], Peter H. Hagedorn [aut]

Maintainer: Marianna Plucinska <marianna.plucinska at roche.com>

Citation (from within R, entercitation("XNAString")):

Installation

To install this package, start R (version "4.5") and enter:

if (!require("BiocManager", quietly = TRUE))    install.packages("BiocManager")BiocManager::install("XNAString")

For older versions of R, please refer to the appropriateBioconductor release.

Documentation

Reference ManualPDF

Need some help? Ask on the Bioconductor Support site!

Details

biocViewsAlignment,Genetics,SequenceMatching,Sequencing,Software
Version1.18.0
In Bioconductor sinceBioC 3.13 (R-4.1) (4.5 years)
LicenseGPL-2
DependsR (>= 4.1)
Importsutils,Biostrings,pwalign,BSgenome,data.table,GenomicRanges,IRanges, methods,Rcpp,stringi,S4Vectors,future.apply,stringr,formattable, stats
System Requirements
URL
See More
SuggestsBiocStyle,knitr,rmarkdown,markdown,testthat,BSgenome.Hsapiens.UCSC.hg38,pander
Linking ToRcpp
Enhances
Depends On Me
Imports Me
Suggests Me
Links To Me
Build ReportBuild Report

Package Archives

FollowInstallation instructions to use this package in your R session.

Source Package
Windows Binary (x86_64)
macOS Binary (x86_64)
macOS Binary (arm64)
Source Repositorygit clone https://git.bioconductor.org/packages/XNAString
Source Repository (Developer Access)git clone git@git.bioconductor.org:packages/XNAString
Package Short Urlhttps://bioconductor.org/packages/XNAString/
Package Downloads ReportDownload Stats

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