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Numbers 21:8,9
And the LORD said unto Moses, Make thee a fiery serpent, and set it upon a pole: and it shall come to pass, that every one that is bitten, when he looketh upon it, shall live…

2 Chronicles 20:12
O our God, wilt thou not judge them? for we have no might against this great company that cometh against us; neither know we what to do: but our eyesare upon thee.

Psalm 22:17
I may tell all my bones: they lookand stare upon me.

for

Isaiah 45:12
I have made the earth, and created man upon it: I,even my hands, have stretched out the heavens, and all their host have I commanded.

John 10:28-30
And I give unto them eternal life; and they shall never perish, neither shall anyman pluck them out of my hand…

Titus 2:13
Looking for that blessed hope, and the glorious appearing of the great God and our Saviour Jesus Christ;

all the ends of the earth
This phrase highlights the universal scope of God's salvation plan. It is not limited to Israel but extends to all nations, fulfilling the promise to Abraham that through his offspring all nations would be blessed (Genesis 12:3). This global vision is consistent with the prophetic literature, where the nations are often called to recognize the sovereignty of Israel's God (Psalm 22:27). In the New Testament, this is realized in the Great Commission (Matthew 28:19), where Jesus commands His disciples to make disciples of all nations, indicating the inclusivity of the gospel message.

for I am God
This declaration asserts the uniqueness and sovereignty of God. In the historical context of Isaiah, Israel was surrounded by polytheistic cultures, and this statement serves as a reminder of the monotheistic faith of Israel. The assertion "I am God" is a recurring theme in Isaiah, emphasizing God's supreme authority and power over all creation (Isaiah 44:6). It also serves as a polemic against the idols and false gods of the surrounding nations, which are powerless and cannot save (Isaiah 46:9-10).

and there is no other
This phrase reinforces the exclusivity of God, a central tenet of the Shema, the Jewish declaration of faith found inDeuteronomy 6:4: "Hear, O Israel: The LORD our God, the LORD is one." It underscores the futility of idolatry and the absolute sovereignty of God. In the New Testament, this exclusivity is affirmed in passages likeJohn 14:6, where Jesus declares Himself the only way to the Father, andActs 4:12, which states that salvation is found in no one else. This exclusivity is a cornerstone of biblical theology, affirming that there is no other name or power by which humanity can be saved.

God’s first word is an urgent invitation. He does not say, “Try harder” or “Work your way up,” but “Turn.”

• Turning is a change of direction—away from sin and self toward the Lord Himself (Isaiah 55:6-7;Zechariah 1:3).

• It requires personal response; no one can turn for someone else (Acts 3:19).

• The initiative is God’s. He speaks first, opening the door for all who will listen (Revelation 3:20).

Turning has a goal: salvation.

• Salvation is rescue from the penalty, power, and ultimately the presence of sin (Romans 6:23;Ephesians 2:8-9).

• It is God’s work, not human achievement (Titus 3:4-5).

• The promise is certain; those who turn are not merely offered help—they “be saved” (John 3:16-17).

The invitation is global and inclusive.

• From the beginning God intended blessing for “all families of the earth” (Genesis 12:3).

• The Psalmist foresaw nations remembering and turning to the LORD (Psalm 22:27-28).

• In Christ this reaches its climax: “a great multitude… from every nation” standing before the throne (Revelation 7:9-10).

The call rests on who He is.

• His absolute existence backs every promise (Exodus 3:14).

• He alone has power to save; idols are powerless, people are helpless (Isaiah 46:9-10).

• Knowing Him is eternal life itself (John 17:3).

Exclusivity is not arrogance but truth.

• The LORD declares, “Besides Me there is no God” (Isaiah 44:6;Deuteronomy 4:35).

• In the New Testament the same exclusivity centers on Jesus: “There is no other name under heaven… by which we must be saved” (Acts 4:12).

• False gods promise much and deliver nothing; the one true God both promises and fulfills.

Isaiah 45:22 is God’s universal, exclusive, and gracious call. Everyone, everywhere is commanded to turn to Him alone for salvation, because He alone is God. The verse presents a simple choice: turn and be saved, or cling to empty substitutes and remain lost. The promise stands open today; the only right response is to turn now, trust fully, and rejoice in the God who saves.