DOI:10.1007/BF00685305 - Corpus ID: 6942826
The arterial lesions underlying lacunes
@article{Fisher1969TheAL, title={The arterial lesions underlying lacunes}, author={C. Miller Fisher}, journal={Acta Neuropathologica}, year={1969}, volume={12}, pages={1-15}, url={https://api.semanticscholar.org/CorpusID:6942826}}- C. Fisher
- Published inActa Neuropathologica1 March 1969
- Medicine
There was a total occlusion of the artery supplying the territory of the infarct in 45 of 50 consecutive lacunes, and segmental arterial disorganization has been discussed in some detail.
494 Citations
494 Citations
Lacunar Infarction and Small Vessel Disease: Pathology and Pathophysiology
- L. Caplan
- 2015
Medicine
Two major vascular pathologies underlie brain damage in patients with disease of small size penetrating brain arteries and arterioles; 1) thickening of the arterial media and 2) obstruction of the…
Lacunar versus non-lacunar syndromes.
- S. MicheliF. Corea
- 2012
Medicine
These findings suggest that lacunar stroke is not always a benign disease, and clinical features may be significant in terms of disability in lacunae in close proximity to crucial anatomical site.
Expanding Cerebellar Lacunes Due to Dilatation of the Perivascular Space Associated With Binswanger's Subcortical Arteriosclerotic Encephalopathy
- N. Benhaiem‐Sigaux
- 2005
Medicine
An 80-year-old hypertensive woman developed right hemiplegia and died 24 hours after admission, and multiple cerebral infarcts of various ages and diffuse subcortical arteriosclerotic encephalopathy were revealed, suggesting a common pathophysiologic mechanism possibly including an alteration of the blood-brain barrier.
Should patients with lacunar stroke and severe carotid artery stenosis undergo endarterectomy?
The concept of lacunar infarction has been long recognized, but it was Fisher who first drew attention to the association with distinct clinical syndromes, and the evidence that patients with LI are likely to benefit from this procedure is searched.
PROGRESS IN CEREBROVASCULAR DISEASE Lacunes
- 2008
Medicine
In 29 of the 30 cases a lesion was found which could explain the PMH, and it is suggested that type HI involves the territory of the internal lenticulostriate branches of the anterior cerebral artery.
Spuriously Large Subcortex Infarct due to Confluent Smaller Lesions: A Diffusion-Weighted MRI/CT Study
A case with two small lacunes seen on diffusion-weighted MRI that merged to form a giant lacunar infarct seen on CT is reported, which is believed to provide CT documentation of the pathogenesis of giant Lacunar Infarcts.
Lacunar Infarction
- B. Norrving
- 2004
Medicine
Several studies using diffusion-weighted MRI (dwMRI) show that a small subcortical ischemic area corresponding to the territory of a penetrating artery is the most common finding, being present in 84% to 94% of patients with a lacunar syndrome.
Circle of Willis Configuration Does Not Predict Early Neurological Deterioration in Lacunar Stroke
- Farid KhasiyevMaya PanditMinghua LiuR. Marshall
- 2025
Medicine
Distribution of lacunes in cerebral amyloid angiopathy and hypertensive small vessel disease
- M. PasiG. BoulouisM. Gurol
- 2017
Medicine
Lobar lacunes seem to have a close relationship with WMH, suggesting a possible common origin, and lobar lacunes are associated with CAA, whereas deep Lacunes are more frequent in HTN-SVD.
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16 References
Lacunes
- Fisher Cm
- 1965
Medicine
While it was possible to correlate lacunes with the occurrence of cerebral atherosclerosis and arterial hypertension, the clinical details in the cases were so deficient that a good clinicopathologic correlation could not be made.
Hypertensive fibrinoid arteritis of the brain and gross cerebral hemorrhage: a form of "hyalinosis".
The infarct, an area of necrosis due to ischemia, may be associated with a varying degree of hemorrhage in the form of isolated or confluent petechiae, and this hemorrhage may be minimal, moderate, or severe in degree.
Untersuchungen und Bemerkungen zur Lehre von der hypertonischen apoplektischen Hirnblutung
- K. Wolff
- 2005
Medicine
In der Lehre yon der hypertonischen apoplektischen t t irnblutung (h. a .H. a.) stehen sieh die Ansichten nach wie vor sehroff gegeniiber, sollen die Ergebnisse dieser Arbeit zeigen.
Die Gehirngefäße beim Hochdruck
Einleitung. Im folgenden soll der Einflul~ einer liinger dauernden Hypertonie auf die Gehirngefi~e untersucht werden. Wir werden uns fragen: welche Ver~nderungen verursacht der Hochdruck an den…
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