Personality changes in Alzheimer's disease: a systematic review

@article{RobinsWahlin2011PersonalityCI,  title={Personality changes in Alzheimer's disease: a systematic review},  author={Tarja-Brita Robins Wahlin and Gerard J. Byrne},  journal={International Journal of Geriatric Psychiatry},  year={2011},  volume={26},  url={https://api.semanticscholar.org/CorpusID:40949990}}
The objective of this study was to review studies of personality change in AD and to assist with the timely diagnosis of AD.

136 Citations

Relationships between big‐five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease

The Dominantly Inherited Alzheimer Network (DIAN) provides a unique cohort in which to relate measures of personality traits to in vivo markers of disease in a much younger sample than in typical late onset AD.

Psychopathology Changes in Alzheimer’s Disease

A higher global personality disorder index and greater incidence of clusters C (anxious) and A (odd/eccentric) are confirmed as personality changes and their implications for the study of psychopathology changes in Alzheimer's disease are discussed.

Personality and Alzheimer’s Disease: An Integrative Review

The article concludes with the implications of personality research for identifying those at greater risk of AD and the potential of personality-tailored interventions aimed at the prevention and treatment of AD.

Personality and Dementia

The goal was to review scientific literature on the association between personality and dementia and found that Premorbid personality might be a determining factor so that caricature or exaggeration of original personality emerges as dementia progresses.

Changes in personality traits in patients with Alzheimer's Disease

This research draws the attention of family members and health professionals to changes in personality traits or behavior of relatives or patients, because it can reflect an underlying neurodegenerative process.

Aspects of Personality Traits and Changes in Different Stages of Dementia Disorders

This chapter aims to outline aspects of personality in different stages of the cognitive continuum towards dementia, and may be important information for clinicians and researchers to identify the early signs and distinguish between dementia disorders.

Title : Relations between personality changes and cerebrospinal fluid biomarkers of Alzheimer ' s disease pathology

It is suggested that early and specific changes in personality are associated with cerebral AD pathology and Concentrations of CSF biomarkers, additionally to severity of the cognitive impairment, significantly contribute in predicting specific personality changes.

Personality Change in the Preclinical Phase of Alzheimer Disease

No evidence for preclinical change in personality before the onset of mild cognitive impairment or dementia was identified, providing evidence against the reverse causality hypothesis and strengthen evidence for personality traits as a risk factor for dementia.

Personality Phenomena in Women with Alzheimer’s Dementia

In terms of both premorbidity and current studies, the relevance of the dimensions neuroticism and conscientiousness, are the most common explanations found in the personality disorder scales, DSM clusters, Appendix B and the global personality disorder index.
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32 References

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Discriminant function analysis showed that the Global Deterioration Scale, the Clinical Rating Scale for Symptoms of Psychosis in Alzheimer's Disease, and the duration of dementia symptoms were the best predictors to classify personality change in an overall score of personality.

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It is demonstrated that patients with DAT become more passive, more coarse, and less spontaneous as a result of the disease.

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These results strengthen the usefulness of caregiver ratings of personality change of patients with memory problems who cannot be useful informants on their own behalf.

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The results indicate that changes in behavior and personality can be reliably reported by family caregivers of patients with mild dementia.

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Both primary caregivers and others who know a patient well may serve as informants for studies of personality in dementia, and substantial agreement between independent raters is indicated.

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