Experimental Transmission of a Kuru-like Syndrome to Chimpanzees

@article{Gajdusek1966ExperimentalTO,  title={Experimental Transmission of a Kuru-like Syndrome to Chimpanzees},  author={D. Carleton Gajdusek and Clarence J. Gibbs and Michael P. Alpers},  journal={Nature},  year={1966},  volume={209},  pages={794-796},  url={https://api.semanticscholar.org/CorpusID:39242676}}

816 Citations

The Structural Basis of Prion Disease Susceptibility and the Transmission Barrier

Using a novel method of two-wavelength CD analysis, it could be shown that recombinant PrP from prion-susceptible species have a higher propensity to refold to the β-state than resistant species.

Prion-like properties of disease-relevant proteins in amyotrophic lateral sclerosis

The current evidence for the role of prion-like mechanisms in classical neurodegenerative diseases and ALS in particular is reviewed and an intriguingly central role of the protein TDP-43 is discussed in the majority of cases of this devastating disease.

Mortuary practices, genetics and other factors relevant to the transmission of kuru in Papua New Guinea

The main thrust of the thesis is on the ethnographic study of mortuary practices, firstly for its primary data, and secondly for its relevance to the transmission of kuru, which can satisfactorily explain the spread and changing epidemiological patterns ofkuru.

Approche palliative des maladies de Creutzfeldt-Jakob. Expérience des services de neurologie et de soins palliatifs des C.H.U. français entre 2005 et 2010

Les maladies de Creutzfeldt-Jakob repondent aux criteres palliatifs des l'annonce dudiagnostic de probabilite. Elles entrainent des repercussions psycho-socio-familialesimportantes. Une approche

Introduction

The conference celebrating ‘The end of kuru: 50 years of research into an extraordinary disease’ was held in the Kohn Room of the Royal Society, London on 11–12 October 2007. It was an extraordinary

8 Transmissible Spongiform Encephalopathies

Diagnosis of a specific neurodegenerative disease may be misleading, as there is both clinical and neuropathologic overlap among diseases and existing diagnostic tools are not always accurate.

Bioassays and Inactivation of Prions.

Cell and animal models that recapitulate some of the key features of cell-to-cell spreading and distinct strains of prions can now be measured.

Prion disease: experimental models and reality

A historical overview of the use of models of prion disease is given, how they have evolved alongside the scientific questions, and how advancements in technologies have pushed the boundaries of the authors' understanding of prions biology are given.

Einfluss der Kupferbindung an der Aminosäureposition 95 im Prionprotein auf den Krankheitsverlauf nach Prioninfektion

Prionerkrankungen gehoren zu den neurodegenerativen Erkrankungen und konnen sowohl genetisch ubertragen als auch erworben werden. Sie verlaufen bisher ausschlieslich letal. Verursacht werden sie
...

4 References

Related Papers

Showing 1 through 3 of 0 Related Papers