HLA genes in Southern Tunisians (Ghannouch area) and their relationship with other Mediterraneans.

@article{Hajjej2006HLAGI,  title={HLA genes in Southern Tunisians (Ghannouch area) and their relationship with other Mediterraneans.},  author={Abdelhafidh Hajjej and Slama Hmida and Houda K{\^a}abi and Amel Dridi and Afef Jridi and A El Gaa l ed and Kamel Boukef},  journal={European journal of medical genetics},  year={2006},  volume={49 1},  pages={          43-56        },  url={https://api.semanticscholar.org/CorpusID:38989276}}

40 Citations

HLA alleles and haplotypes in Sudanese population and their relationship with Mediterraneans

Results found show that Nubians are genetically related with African Sub-Saharan populations and distant from other Sudanese tribes, who are closer to Mediterranean populations than to Sub-Saharan ones.

The investigation of the origin of Southern Tunisians using HLA genes

A limited genetic contribution of Arab invasion and Black caravans on the makeup of Southern Tunisian gene pool is indicated, and Southern Tunisians appear to be closely related to others Tunisian populations including Berbers, North Africans and Iberians.

HLA-DRB1 frequencies of the Comorian population and their genetic affinities with Sub-Saharan African and Indian Oceanian populations

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HLA Class I and Class II Alleles and Haplotypes Confirm the Berber Origin of the Present Day Tunisian Population

HLA genotype results indicate that Tunisians are related to present-day North Africans, Berbers and to Iberians, but not to Eastern Arabs (Palestinians, Jordanians and Lebanese).

HLA Class II Allele and Haplotype Diversity in Libyans and Their Genetic Relationships with Other Populations

Libyans appear to be closely related to North Africans, Saudis, and Iberians, but distinct from Levantine Arabs, East Mediterraneans, and Sub-Saharan Africans, which indicates limited genetic contribution of Levantine Arab and sub-Saharans on the makeup of Libyan gene pool.

HLA class I and class II polymorphisms in Tunisian Berbers

A higher proportion of Iberian than Arab ancestry in Tunisian Berbers is indicated, indicating that the Arab invasion of North Africa did not significantly impact the genetic makeup of North Africans and that the main part of their genetic pool came after the Northward Saharan migration.

HLA class I and class II polymorphism in a population from south‐eastern Tunisia (Gabes Area)

The successive invasions of North Africa in general and Tunisia in particular did not modify markedly the genetic makeup of present‐day Tunisians, and with the exception of Greeks who have a sub‐Saharan genetic profile, all Mediterranean populations depict a typical mediterranean substratum.

The Northern Migrations from a drying Sahara (6,000 years BP): cultural and genetic influence in Greeks, Iberians and other Mediterraneans

Greeks have a Sub-Saharan gene input according to HLA and other autosomic markers. Iberians, Canarians, and North Africans show a close genetic relatedness. This is concordant with a drying humid

30 References

The origin of Cretan populations as determined by characterization of HLA alleles.

The results indicate that the Indoeuropean Greeks may be considered as a Mediterranean population of a more recent origin (after 2000 B.C.), while all other studied Mediterraneans (including Cretans) belong to an older substratum which was present in the area since pre-Neolithic times.

HLA genes in Macedonians and the sub-Saharan origin of the Greeks.

Genetic distances are closer between Greeks and Ethiopian/ sub-Saharan groups than to any other Mediterranean group and Greeks cluster with Ethiopians/sub-Saharans in both neighbour joining dendrograms and correspondence analyses.

HLA alleles and haplotypes in the Turkish population: relatedness to Kurds, Armenians and other Mediterraneans.

It is concluded that this invasion had a relatively few invaders in comparison to the already settled populations, i.e. Anatolian Hittite and Hurrian groups (older than 2000 B.C.), which may have given rise to present-day Kurdish, Armenian and Turkish populations.

Population genetic relationships between Mediterranean populations determined by HLA allele distribution and a historic perspective.

HLA genomics shows that Greeks share an important part of their genetic pool with sub-Saharan Africans (Ethiopians and west Africans) also supported by Chr 7 Markers and Kurds and Armenians are genetically very close to Turks and other Middle East populations.

West Mediterranean islands (Corsica, Balearic islands, Sardinia) and the Basque population: contribution of HLA class I molecular markers to their evolutionary history.

The genetic structure of Balearic islands (Corsica and Sardinia) were compared and their position among the neighbouring Caucasian populations was inferred and some common haplotypes in the populations of the islands that confirm the results of the phylogenetic analysis and could be related to their history.

HLA alleles in isolated populations from North Spain: origin of the Basques and the ancient Iberians.

HLA-A, -B, -DRB1, -DQA1 and -DQB1 alleles have been studied in three relatively isolated populations of northern Spain and compared with neighbouring ones and other Mediterraneans by using neighbour-joining dendrograms and plane genetic distances.

HLA genes in Arabic-speaking Moroccans: close relatedness to Berbers and Iberians.

The HLA data suggest that most Moroccans are of a Berber (Imazighen) origin and that Arabs who invaded North Africa and Spain in the 7th century A.D. did not substantially contributed to the gene pool; however, they imposed their advanced culture and their religion.

Comparative analysis of HLA polymorphism at the serologic and molecular level in Moroccan and Ashkenazi Jews.

Comparison between their HLA profiles and those of non-Jews revealed that the Jewish groups in some aspects resembled one another but in others showed disparities.

HLA class I and class II DNA typing and the origin of Basques.

The range of possibilities provided by the highly polymorphic HLA system is stressed by using genetic distances, phylogenetic trees and principal component analyses in order to reconstruct population history.

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