Benign Multinodular Goiter

@article{Frilling2004BenignMG,  title={Benign Multinodular Goiter},  author={Andrea Frilling and C. Liu and Frank Weber},  journal={Scandinavian Journal of Surgery},  year={2004},  volume={93},  pages={278 - 281},  url={https://api.semanticscholar.org/CorpusID:38834260}}
Theobservation that TSH-suppressive treatment may causeareduc-tion of goiter volume underlines the role of TSH asgoitrogenfactor.

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Alteration of Trace Elements in Multinodular Goiter, Thyroid Adenoma, and Thyroid Cancer

It was found that Cu/Zn and U/Se ratios had significantly increased values in pathological blood samples leading to the possibility of establishing new circulating screening markers, which can represent significant translational information since these diseases are widespread and the diagnostic procedure is still difficult.

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The present study carried out in a government notified endemic region to evaluate the nontoxic goiter patients for pattern of presentation, histopathological causes, with its surgical management and post-operative complications.

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Most of the multinodular goiters are hyperthyroidism and the base line treatment is only surgical, and the risk factors were TPO-Ab.

Determination of Fifty Trace Element Contents in Macro and Micro Follicular Colloid Nodular Goiter

It was found that with a goitrous transformation the Ag, Al, B, Bi, Co, Er, Fe, Hg, Mo, Nd, Ni, Pb, Pr, Rb, Tl, U, Y, and Zn level in thyroid tissue can be significantly changed, and these changes depend on CNG histology.

Non Toxic Goiter: Cytology, Histological Analysis: A Study in Mosul

The histological findings observed in non toxic goiter of the resected thyroid tissue in Mosul city were compared with the results of Fine Needle Aspiration Cytology to assess the role of this method in the early diagnosis & correct management of both multinodular goiter & solitary thyroid nodule.

Determination of twenty chemical element contents in macro-and micro-follicular colloid goiter using neutron activation analysis and inductively coupled plasma atomic emission spectrometry

There are considerable changes in ChE contents in the goitrous transformed tissue of thyroid, which depend on the histology of goiter, and these changes depend on CNG histology.

ANTI - THYROID PEROXIDASE A NTI BODY LEVEL IN THYROI D NODUL ES: WITH SPECIAL REFERENCE TO THYROID NEOPLASIA

Anti - TPO antibody level was increased in Benign & toxic form of Multi nodular goiter and papillary carcinoma but there is no elevation of Anti - T PO antibody level in follicular adenoma or follicular carcinoma.

Size and Duration of Multinodular Goiter Predicts Its Toxicity

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19 References

Radioiodine for nontoxic multinodular goiter.

It is shown that 131I treatment of nontoxic nodular goiter results in a mean thyroid volume reduction of 40% after 1 year of 50-60% after 3-5 years, and an improvement of compressive symptoms can be achieved, as measured by MRI.

Management of the nontoxic multinodular goiter: a North American survey.

In the work-up of patients with nontoxic multinodular goiter, ATA clinicians employ determinations of TSH often combined with a T4 and/or T3 assay and antithyroid peroxidase antibodies.

Management of simple nodular goiter: current status and future perspectives.

It is of the view that levothyroxine, although widely used, should no longer be recommended routinely for this condition and the increasing use of fine-needle aspiration biopsy is supported.

Reduction in goiter size by 131I therapy in patients with non-toxic multinodular goiter.

131I treatment of non-toxic goiter is an effective treatment at the expense of post-radiation (subclinical) hypothyroidism in patients with non-Toxic multinodular goiter.

The advantage of total thyroidectomy to avoid reoperation for incidental thyroid cancer in multinodular goiter.

Recommend total or near-total thyroidectomy in multinodular goiter to eliminate the necessity for early completion thyroidectomyIn case of a final diagnosis of thyroid cancer.

Total Thyroidectomy for Benign Thyroid Disorders in an Endemic Region

Total thyroidectomy should be considered a treatment of choice for multinodular goiter and Graves' disease in a setting of palpable nodule(s) or ophthalmopathy (or both), particularly relevant in endemic regions where patients present with a long-standing, large nodularGoiter with virtually no normal thyroid tissue.

Total thyroidectomy for bilateral benign multinodular goiter: effect of changing practice.

Examining the changing pattern of use of bilateral subtotal thyroidectomy and total thyroidectomy in the initial surgical treatment of nodular goiter in Australia and New Zealand concluded thattotal thyroidectomy is a safe and effective treatment for bilateral BMNG, and it is now the routine procedure throughout Australia andNew Zealand.

Prospective Study of Postoperative Complications After Total Thyroidectomy for Multinodular Goiters by Surgeons With Experience in Endocrine Surgery

In endocrine surgery units, TT can be performed for MG with a definitive complication rate of around 1%; the main independent risk factors for the development of complications are hyperthyroidism and goiter size.

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