DOI:10.1007/s12020-014-0298-7 - Corpus ID: 22669723
Selenium supplementation and the risk of type 2 diabetes mellitus: a meta-analysis of randomized controlled trials
@article{Mao2014SeleniumSA, title={Selenium supplementation and the risk of type 2 diabetes mellitus: a meta-analysis of randomized controlled trials}, author={Song Mao and Aihua Zhang and Songming Huang}, journal={Endocrine}, year={2014}, volume={47}, pages={758-763}, url={https://api.semanticscholar.org/CorpusID:22669723}}- Song MaoA. ZhangSongming Huang
- Published inEndocrine25 May 2014
- Medicine
- Endocrine
The findings do not support the routine application of Se supplementation for T2DM prevention in Caucasians and larger studies are needed to investigate the effects of Se supplements on T2 DM prevention among various populations and further elucidate the impact of age and study length.
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43 Citations
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Overall, this meta-analysis showed that selenium administration may lead to an improvement in insulin and QUICKI, but did not affect FPG, HOMA-IR, and lipid profiles.
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A comprehensive meta-analysis of studies on the association between selenium (Se) and diabetes mellitus (DM) demonstrates that high levels of Se are associated with the presence of DM.
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Overall, the association between dietary factors and type 2 diabetes has been extensively studied, but few of the associations were graded as high quality of evidence.
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