DOI:10.1111/jnc.12940 - Corpus ID: 21621635
Larvae of the small white butterfly, Pieris rapae, express a novel serotonin receptor
@article{Qi2014LarvaeOT, title={Larvae of the small white butterfly, Pieris rapae, express a novel serotonin receptor}, author={Yi-xiang Qi and Ren-ying Xia and Ya-su Wu and David Stanley and Jia Huang and Gōngy{\'i}n Y{\`e}}, journal={Journal of Neurochemistry}, year={2014}, volume={131}, pages={767 - 777}, url={https://api.semanticscholar.org/CorpusID:21621635}}- Y. QiRen-ying XiaG. Yè
- Published inJournal of Neurochemistry1 December 2014
- Biology
It is inferred that Pr5‐HT8 represents the first recognized member of a novel 5‐HT receptor class with a unique pharmacological profile and is likely to be an invertebrate‐specific receptor because there were no similar receptors in mammals.
31 Citations
31 Citations
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Serotonin (5‐hydroxytryptamine, 5‐HT) is an important biogenic amine in insects, which regulates and controls many important physiological and behavioral processes by binding to different G…
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The results suggest that the Pv5-HT7 receptor may have specific functions in regulating the development of P. vicina, especially in adult formation and caste differentiation, feeding and caring behaviors of workers in the nest, and in theDevelopment of motor organs and mating behaviors in males.
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An overview of heterologously expressed receptors is provided, which considers evolutionary relationships among them, classification based on these relationships and nomenclature that reflects classification, and transduction pathways and pharmacological profiles are compared.
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A separate serotonin receptor type may mediate cardiomodulatory effects controlled by serotonin in R. prolixus, which shares sequence similarity to the vertebrate serotonin type 2 receptors, and a distinct agonist/antagonist profile is indicated.
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The isolation of a cDNA coding for a Drosophila melanogaster serotonin receptor that displays a sequence, a gene organization, and pharmacological properties typical of the mammalian 5-HT2 serotonin receptor subtype is reported.
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