Effect of Secretion of Splenocytes after Superior Ovarian Nerve Section on the Ovarian Steroidogenesis

@article{Forneris1999EffectOS,  title={Effect of Secretion of Splenocytes after Superior Ovarian Nerve Section on the Ovarian Steroidogenesis},  author={Myriam L Forneris and Liliana Beatriz Oliveros and Luis Inocencio Aguado},  journal={Neuroimmunomodulation},  year={1999},  volume={6},  pages={293 - 299},  url={https://api.semanticscholar.org/CorpusID:21043220}}
Functional evidence for modulation of immune function by the sympathetic nervous system and its principal neurotransmitter, NE is shown, suggesting that splenocyte secretions, which participate in the ovarian steroidogenic response, particularly in progesterone release, might be controlled by adrenergic influences.

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Secretion from neuropeptide-treated splenocytes modifies ovarian steroidogenesis.

The ovarian steroidogenic response, which was modified by the effects of an in vivo SON transection on spleen cells, was reverted by an in vitro system in which the splenocytes were treated with VIP or NPY.

Sympathetic innervation regulates macrophage activity in rats with polycystic ovary.

Functional evidence that modulation of the immune-endocrine function by peripheral sympathetic nervous system might have implications for understanding the pathophysiology of PCOS is presented.

Role of the central and peripheral nervous system in the ovarian function

    L. Aguado
    Medicine, Biology
    Microscopy research and technique
  • 2002
This review attempts to give a comprehensive overview of ovarian innervation, considering the whole nervous system and its different levels that may modify the ovarian function. The connection…

37 References

Prepubertal ovarian function is finely regulated by direct adrenergic influences. Role of noradrenergic innervation.

The results suggest that during prepubertal maturation, noradrenergic fibers reaching the ovary via the SON may modify ovarian steridogenic sensitivity to catecholamines, by regulating the number of functional beta- adrenergic receptors in the gland.

Ovarian adrenergic nerves play a role in maintaining preovulatory steroid secretion.

It is suggested that neural impulses, possibly adrenergic, which reach the ovary via the SON contribute to the maintenance of gonadotropin-supported secretion of ovarian steroids on the day of proestrus.

OVARIAN ADRENERCIC NERVES PLAY A ROLE IN MAINTAINING PREOVULATORY STEROID SECRETION1

It is suggested that neural impulses, possibly adrenergic, which reach the ovary via the SON contribute to the maintenance of progesterone and estradiol secretion in the proestrous and estrous phases of the rat estrous cycle.

Effect of selective removal of the adrenal medulla on female sexual development.

It is suggested that EPI of adrenomedullary origin supports female prepubertal development by stimulating ovarian P secretion, favoring Prl and GH release and amplifying the stimulatory effect of low gonadotropin levels on ovarian steroidogenesis.

Is ovarian adrenergic innervation essential to gonadal function in adult rats?

The view that ovarian sympathetic innervation contributes to the regulation of the prepubertal development of the ovarian functions is reinforced.

Prepubertal rat ovary: hormonal modulation of beta-adrenergic receptors and of progesterone response to adrenergic stimulation.

In the present study, experiments have been conducted to determine if hormones other than follicle stimulating hormone (FSH) that are known to be involved in regulating prepubertal ovarian function can mimic the facilitatory effect of FSH on progesterone (P) response of granulosa cells to beta-adrenergic stimulation.

The origin of the extrinsic adrenergic innervation to the rat ovary

It is concluded that the extrinsic adrenergic nerves to the rat ovary reach the organ by two routes: one via the nerve in the suspensory ligament (superior ovarian nerve), and one through the traditionally described ovarian plexus along the ovarian artery.

Lymphokines from concanavalin-A-stimulated lymphocytes regulate rat granulosa cell steroidogenesis in vitro.

The present studies demonstrate that secretory products of lymphocytes (collectively termed lymphokines) can affect steroidogenesis in cultured rat granulosa cells, implying that immune cell factors may play a significant role in the differentiation and maturation of granULosa cells.

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