Spindle model responsive to mixed fusimotor inputs and testable predictions of beta feedback effects.

@article{Maltenfort2003SpindleMR,  title={Spindle model responsive to mixed fusimotor inputs and testable predictions of beta feedback effects.},  author={Mitchell Gil Maltenfort and Robert E Burke},  journal={Journal of neurophysiology},  year={2003},  volume={89 5},  pages={          2797-809        },  url={https://api.semanticscholar.org/CorpusID:18253128}}
A computationally efficient model of group Ia afferent behavior, capable of responding to multiple fusimotor inputs, was developed that matched experimental data and the strength of beta feedback, estimated as a "loop gain" was comparable to experimental estimates.

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65 References

Reflex actions of muscle afferents on fusimotor innervation in decerebrated cats: an assessment of beta contributions

The existence of beta innervation in many cat muscles raises the possibility that spindle afferent discharge will excite beta motoneurons, augmenting spindleAfferent discharge and thereby closing a positive feedback loop, and the contribution of such a beta configuration to reducing the sensitivity of muscle to changes in load and muscle properties is evaluated.

Beta-contributions to fusimotor action in triceps surae muscles of decerebrated cats.

It appears likely that beta-motoneurons are able to produce both static and dynamic effects above extrafusal threshold, but that the actions require on-going gamma-activity in order to be effective.

A muscle spindle model for primary afferent firing based on a simulation of intrafusal mechanical events.

A muscle spindle model for primary afferent firing is presented that contains two components representing a gamma d-dependent and gamma s-dependent intrafusal fiber, and provides insight into how intraFusal events may contribute to observed firing properties of real muscle spindles.

Activation of cat muscle spindles by static skeletofusimotor axons.

The persistence ofstatic beta‐driving after suppression of extrafusal contraction provided evidence for its intrafusal origin, and driving elicited by static beta‐axons could persist during changes in muscle length, but small fluctuations in the delay between each impulse and the preceding stimulus were observed.

The use of sinusoidal and ramp stretch stimuli in characterizing fusimotor effects on cat muscle spindles

Comparisons were made between the results of testing muscle spindle primary afferents with low‐frequency, large‐amplitude sine waves of muscle stretch and with repeating ramp‐and‐hold stretches, showing that it is important to recognize the different effects of chain and bag2 intrafusal fibre activation as components of static fusimotor excitation.

Response characteristics of muscle spindle endings at constant length to variations in fusimotor activation.

The aim of the present investigation was to determine the transfer function between fusimotor stimulus rate and afferent impulse frequency of muscle spindles at constant length and all combinations of fusicotor fibres and spindle endings were equivalent.

Models of ensemble firing of muscle spindle afferents recorded during normal locomotion in cats

Length was predicted very accurately from firing profiles with the inverse of the above models, indicating that the nervous system could in principle process spindle firing in a relatively simple way to give accurate information on muscle length.

A model of spindle afferent response to muscle stretch.

A unified model of the properties of stretch responses of mammalian spindle endings is proposed that mimics qualitatively the observed fusimotor effects not only on the response to large ramp stretch but also the contrasting effects seen with smaller, sinusoidal stretch.

A quantitative study of skeletofusimotor innervation in the cat peroneus tertius muscle.

1. Physiological tests were used to identify skeletofusimotor or beta axons to the cat peroneus tertius muscle in order to assess the proportion of beta axons in the motor supply to this muscle. 2.
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