DOI:10.1111/head.13527 - Corpus ID: 119544256
The Efficacy and Safety of Prochlorperazine in Patients With Acute Migraine: A Systematic Review and Meta‐Analysis
@article{Golikhatir2019TheEA, title={The Efficacy and Safety of Prochlorperazine in Patients With Acute Migraine: A Systematic Review and Meta‐Analysis}, author={Iraj Golikhatir and Hamed Cheraghmakani and Farzad Bozorgi and Fatemeh Jahanian and Mohammad Sazgar and Seyed Hossein Montazer}, journal={Headache: The Journal of Head and Face Pain}, year={2019}, volume={59}, url={https://api.semanticscholar.org/CorpusID:119544256}}- Iraj GolikhatirH. CheraghmakaniSeyed Hossein Montazer
- Published inHeadache16 April 2019
- Medicine
The aim of this review was to evaluate the efficacy and safety of prochlorperazine (PCP) in patients with acute migraine headache in the emergency department (ED).
27 Citations
27 Citations
The effectiveness of parenteral agents for pain reduction in patients with migraine presenting to emergency settings: A systematic review and network analysis
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To assess the comparative effectiveness and safety of parenteral agents for pain reduction in patients with acute migraine.
Prochlorperazine for treatment of acute migraines in adults.
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Migraine headache results in over 1 million emergency department visits per year in the United States.1-3 Several treatments have been offered to treat the headache.4-6 Prochlorperazine has been…
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Korolac appears to be a safe and well-tolerated means of controlling pain in patients with primary headache in emergency departments, and has a pronounced effect that is even more pronounced within 1 hour after application and 2 hours later.
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Korolac appears to be a safe and well-tolerated means of controlling pain in patients with primary headache in emergency departments, and has a pronounced effect that is even more pronounced within 1 hour after application and 2 hours later.
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Intranasal lidocaine can be considered a useful option for patients with an acute migraine because it yields a high success rate, a low pain intensity, an infrequent need for rescue medicine, and tolerable adverse events.
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Intranasal ketamine and intravenous ketorolac both effectively reduced headaches, however, more analgesic effects of intranasAL ketamine in a short time can be considered as a selective approach to reducing headaches.
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Dopamine receptor antagonists, such as metoclopramide and prochlorperazine, were the most efficacious in terminating migraines in the studies examined.
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This work addressed two clinically relevant questions: which injectable medications should be considered first‐line treatment for adults who present to an ED with acute migraine and do parenteral corticosteroids prevent recurrence of migraine in adults discharged from an ED.
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Objective.— The final section of this 3‐part review analyzes published reports involving the acute treatment of migraine with opioids, non‐steroidal anti‐inflammatory drugs (NSAIDs), and steroids in…
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