DOI:10.1007/BF00691095 - Corpus ID: 10920322
Pathophysiological aspects of brain edema
@article{Klatzo2004PathophysiologicalAO, title={Pathophysiological aspects of brain edema}, author={Igor Klatzo}, journal={Acta Neuropathologica}, year={2004}, volume={72}, pages={236-239}, url={https://api.semanticscholar.org/CorpusID:10920322}}- I. Klatzo
- Published inActa Neuropathologica2004
- Medicine
A biphasic opening of the blood-brain barrier, associated with vasogenic edema, is observed following release of major cerebral artery occlusion, and is associated with a severe ischemic brain tissue injury.
248 Citations
248 Citations
Pathophysiological and pathochemical aspects of cerebral edema
- A. Baethmann
- 2005
Medicine
Studies on resolution of vasogenic edema provided insight into the problem of how brain tissue manages to regain control over its extracellular environment, and most of the therapeutic methods currently in use have not been shown to interfere with specific aspects of brain edema.
Pathology and new players in the pathogenesis of brain edema
- S. NagJ. ManiasD. Stewart
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Medicine
Effective treatment of brain edema cannot be achieved by a single agent but will require the administration of a variety of agents released at different times during the course of edema in order to be successful.
Mechanisms of cerebral edema in traumatic brain injury: therapeutic developments
Attenuating blood–brain barrier permeability has become a promising approach to managing brain edema and associated swelling given that increases in cranial water content can only be derived from the vasculature.
Involvement of bradykinin in brain edema development after ischemic stroke
- Marina DobrivojevićK. ŠpiranecAleksandra Sinđić
- 2014
Medicine
The aim of this paper is to summarize the recent research in the field of bradykinin function followed by characterization of different types of brain edema development related to ischemic brain injury, together with the involvement of br Bradykinin in edema formation.
EDEMA-SWELLING OF THE BRAIN IN THE CLINIC OF INFECTIOUS DISEASES: PATHOGENESIS, CLINIC, DIAGNOSIS, TREATMENT
- V. PoltorapavlovV. BodnarO. Zdor
- 2023
Medicine
Bulletin of Problems Biology and Medicine
It is necessary to analyze modern clinical concepts, and diagnostic and treatment strategies, presented in the literature regarding the problems of early diagnosis of cerebral edema, the significance of its clinical definition, and treatment at the pre-hospital and hospital stages.
Aquaporins and blood–brain barrier permeability in early edema development after traumatic brain injury
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Medicine
Aquaporin-4: A Potential Therapeutic Target for Cerebral Edema
- Guanghui TangGuo-Yuan Yang
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Medicine
The latest findings about the effects of mesenchymal stem cells (MSCs) and microRNA-29b on aquaporin-4 are introduced, which could provide powerful intervention tools targeting aquapor in the brain of different pathological disorders.
Mechanisms of Astrocyte-Mediated Cerebral Edema
- J. StokumDavid B. KurlandV. GerzanichJ. Simard
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Medicine, Biology
AQP4 function and localization in the BBB during health and injury is discussed, and post-injury ionic events that modulate AQP4-dependent edema formation are examined.
Introducing the concept of “CSF‐shift edema” in traumatic brain injury
Based on new understandings of the hydrodynamic aspects of cerebrospinal fluid (CSF), an additional mechanism of brain swelling can be considered, termed as “CSF‐shift edema.”
...
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Biology, Medicine
SummaryChanges in morphology, behavior of the blood-brain barrier (BBB), regional cerebral blood flow (rCBF), and local cerebral glucose utilization (LCGU) were assessed and correlated in Mongolian…
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