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6-pyruvoyltetrahydropterin 2'-reductase activity

Term Information

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Accession
GO:0047028
Name
6-pyruvoyltetrahydropterin 2'-reductase activity
Ontology
molecular_function
Synonyms
6-lactoyl-5,6,7,8-tetrahydropterin:NADP+ 2'-oxidoreductase activity, 6-pyruvoyl tetrahydropterin (2'-oxo)reductase activity, 6-pyruvoyl-tetrahydropterin 2'-reductase activity, 6-pyruvoyltetrahydropterin reductase activity, 6PPH4(2'-oxo) reductase activity, pyruvoyl-tetrahydropterin reductase activity
Alternate IDs
None
Definition
Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.Source:EC:1.1.1.220,MetaCyc:1.1.1.220-RXN
Comment
None
History
See termhistory for GO:0047028 at QuickGO
Chem. react.
has participant(6R)-6-lactoyl-5,6,7,8-tetrahydropterin
has participant(R)-dyspropterin
has participanthydron
has participantNADPH(4-)
has participantNADP(3-)
Subset
None
Related
Linkto allgenes and gene products annotated to 6-pyruvoyltetrahydropterin 2'-reductase activity (excluding "regulates").
Linkto all direct and indirectannotationsto 6-pyruvoyltetrahydropterin 2'-reductase activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for 6-pyruvoyltetrahydropterin 2'-reductase activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Parents of 6-pyruvoyltetrahydropterin 2'-reductase activity (GO:0047028)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
6-pyruvoyltetrahydropterin 2'-reductase activity[RO:0000057 relation] RO:0000057 (6R)-6-lactoyl-5,6,7,8-tetrahydropterin (CHEBI:136565)
6-pyruvoyltetrahydropterin 2'-reductase activity[RO:0000057 relation] RO:0000057 (R)-dyspropterin (CHEBI:136564)
6-pyruvoyltetrahydropterin 2'-reductase activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)
6-pyruvoyltetrahydropterin 2'-reductase activity[RO:0000057 relation] RO:0000057 NADPH(4-) (CHEBI:57783)
6-pyruvoyltetrahydropterin 2'-reductase activity[RO:0000057 relation] RO:0000057 NADP(3-) (CHEBI:58349)
6-pyruvoyltetrahydropterin 2'-reductase activity[is_a relation] is_a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)

This term has no children.

EC
1.1.1.220
MetaCyc
1.1.1.220-RXN
RHEA
11772


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