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15-hydroxyprostaglandin dehydrogenase (NADP+) activity

Term Information

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Accession
GO:0047021
Name
15-hydroxyprostaglandin dehydrogenase (NADP+) activity
Ontology
molecular_function
Synonyms
(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate:NADP+ 15-oxidoreductase activity, type II 15-hydroxyprostaglandin dehydrogenase activity, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostaglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase
Alternate IDs
None
Definition
Catalysis of the reaction: NADP+ + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H+ + NADPH.Source:EC:1.1.1.197,RHEA:11636
Comment
None
History
See termhistory for GO:0047021 at QuickGO
Chem. react.
has participantNADP(3-)
has participantNADPH(4-)
has participantprostaglandin E1(1-)
has participant15-dehydro-prostaglandin E1(1-)
has participanthydron
Subset
None
Related
Linkto allgenes and gene products annotated to 15-hydroxyprostaglandin dehydrogenase (NADP+) activity (excluding "regulates").
Linkto all direct and indirectannotationsto 15-hydroxyprostaglandin dehydrogenase (NADP+) activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for 15-hydroxyprostaglandin dehydrogenase (NADP+) activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Graph of GO:0047021 from QuickGO

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Parents of 15-hydroxyprostaglandin dehydrogenase (NADP+) activity (GO:0047021)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[RO:0000057 relation] RO:0000057 NADP(3-) (CHEBI:58349)
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[RO:0000057 relation] RO:0000057 NADPH(4-) (CHEBI:57783)
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[is_a relation] is_a oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616)
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[RO:0000057 relation] RO:0000057 prostaglandin E1(1-) (CHEBI:57397)
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[RO:0000057 relation] RO:0000057 15-dehydro-prostaglandin E1(1-) (CHEBI:57401)
15-hydroxyprostaglandin dehydrogenase (NADP+) activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)

This term has no children.

EC
1.1.1.197
KEGG_REACTION
R04552
MetaCyc
1.1.1.197-RXN
RHEA
11636
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