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5-oxoprolinase (ATP-hydrolyzing) activity

Term Information

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Accession
GO:0017168
Name
5-oxoprolinase (ATP-hydrolyzing) activity
Ontology
molecular_function
Synonyms
5-OPase activity, 5-oxo-L-prolinase activity, 5-oxo-L-proline amidohydrolase (ATP-hydrolysing), 5-oxoprolinase (ATP-hydrolysing), 5-oxoprolinase activity, L-pyroglutamate hydrolase activity, oxoprolinase activity, pyroglutamase (ATP-hydrolysing), pyroglutamase (ATP-hydrolyzing) activity, pyroglutamase activity, pyroglutamate hydrolase activity, pyroglutamic hydrolase activity
Alternate IDs
None
Definition
Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H2O = L-glutamate + ADP + 2 H+ + phosphate.Source:EC:3.5.2.9,RHEA:10348
Comment
None
History
See termhistory for GO:0017168 at QuickGO
Chem. react.
has participantATP(4-)
has participanthydrogenphosphate
has participant5-oxo-L-prolinate
has participanthydron
has participantADP(3-)
has participantwater
has participantL-glutamate(1-)
Subset
None
Related
Linkto allgenes and gene products annotated to 5-oxoprolinase (ATP-hydrolyzing) activity (excluding "regulates").
Linkto all direct and indirectannotationsto 5-oxoprolinase (ATP-hydrolyzing) activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for 5-oxoprolinase (ATP-hydrolyzing) activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Parents of 5-oxoprolinase (ATP-hydrolyzing) activity (GO:0017168)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 ATP(4-) (CHEBI:30616)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 hydrogenphosphate (CHEBI:43474)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 5-oxo-L-prolinate (CHEBI:58402)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 ADP(3-) (CHEBI:456216)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 water (CHEBI:15377)
5-oxoprolinase (ATP-hydrolyzing) activity[RO:0000057 relation] RO:0000057 L-glutamate(1-) (CHEBI:29985)
5-oxoprolinase (ATP-hydrolyzing) activity[is_a relation] is_a hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides (GO:0016812)

This term has no children.

EC
3.5.2.9
KEGG_REACTION
R00251
MetaCyc
5-OXOPROLINASE-ATP-HYDROLYSING-RXN
Reactome
R-HSA-1247935
R-HSA-5603208
RHEA
10348
Wikipedia
5-oxoprolinase_(ATP-hydrolysing)
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