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glutamyl-tRNA reductase activity

Term Information

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Accession
GO:0008883
Name
glutamyl-tRNA reductase activity
Ontology
molecular_function
Synonyms
L-glutamate-semialdehyde: NADP+ oxidoreductase (L-glutamyl-tRNAGlu-forming)
Alternate IDs
None
Definition
Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP+ + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H+ + NADPH.Source:EC:1.2.1.70,RHEA:12344
Comment
None
History
See termhistory for GO:0008883 at QuickGO
Chem. react.
has participant(S)-4-amino-5-oxopentanoic acid zwitterion
has participantAMP 3'-end(1-) residue
has participanthydron
has participantNADPH(4-)
has participantNADP(3-)
has participant3'-(L-glutamate)adenylyl(1-) group
Subset
None
Related
Linkto allgenes and gene products annotated to glutamyl-tRNA reductase activity (excluding "regulates").
Linkto all direct and indirectannotationsto glutamyl-tRNA reductase activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for glutamyl-tRNA reductase activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Graph of GO:0008883 from QuickGO

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Parents of glutamyl-tRNA reductase activity (GO:0008883)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
glutamyl-tRNA reductase activity[is_a relation] is_a catalytic activity, acting on a tRNA (GO:0140101)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 (S)-4-amino-5-oxopentanoic acid zwitterion (CHEBI:57501)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 AMP 3'-end(1-) residue (CHEBI:78442)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 NADPH(4-) (CHEBI:57783)
glutamyl-tRNA reductase activity[is_a relation] is_a oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 NADP(3-) (CHEBI:58349)
glutamyl-tRNA reductase activity[RO:0000057 relation] RO:0000057 3'-(L-glutamate)adenylyl(1-) group (CHEBI:78520)

This term has no children.

EC
1.2.1.70
KEGG_REACTION
R04109
MetaCyc
GLUTRNAREDUCT-RXN
RHEA
12344
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