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oxysterol 7-alpha-hydroxylase activity

Term Information

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Accession
GO:0008396
Name
oxysterol 7-alpha-hydroxylase activity
Ontology
molecular_function
Synonyms
cytochrome P450 CYP7B1
Alternate IDs
None
Definition
Catalysis of the reaction: 7-oxocholesterol + H+ + NADPH = 7alpha-hydroxycholesterol + NADP+.Source:RHEA:68740
Comment
None
History
See termhistory for GO:0008396 at QuickGO
Chem. react.
has participantNADP(3-)
has participant7alpha-hydroxycholesterol
has participantNADPH(4-)
has participanthydron
has participant7-ketocholesterol
Subset
None
Related
Linkto allgenes and gene products annotated to oxysterol 7-alpha-hydroxylase activity (excluding "regulates").
Linkto all direct and indirectannotationsto oxysterol 7-alpha-hydroxylase activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for oxysterol 7-alpha-hydroxylase activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Graph of GO:0008396 from QuickGO

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Parents of oxysterol 7-alpha-hydroxylase activity (GO:0008396)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
oxysterol 7-alpha-hydroxylase activity[RO:0000057 relation] RO:0000057 NADP(3-) (CHEBI:58349)
oxysterol 7-alpha-hydroxylase activity[RO:0000057 relation] RO:0000057 7alpha-hydroxycholesterol (CHEBI:17500)
oxysterol 7-alpha-hydroxylase activity[RO:0000057 relation] RO:0000057 NADPH(4-) (CHEBI:57783)
oxysterol 7-alpha-hydroxylase activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)
oxysterol 7-alpha-hydroxylase activity[is_a relation] is_a steroid 7-alpha-hydroxylase activity (GO:0008387)
oxysterol 7-alpha-hydroxylase activity[RO:0000057 relation] RO:0000057 7-ketocholesterol (CHEBI:64294)

This term has no children.

Reactome
R-HSA-192178
R-HSA-191972
R-HSA-5602885
R-HSA-192065
RHEA
68740
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