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aldose reductase (NADPH) activity

Term Information

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Accession
GO:0004032
Name
aldose reductase (NADPH) activity
Ontology
molecular_function
Synonyms
alditol:NADP+ 1-oxidoreductase activity, aldehyde reductase activity, aldose reductase activity, polyol dehydrogenase (NADP(+)) activity
Alternate IDs
None
Definition
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.Source:EC:1.1.1.21
Comment
None
History
See termhistory for GO:0004032 at QuickGO
Chem. react.
has participantalditol
has participantaldose
has participantNADPH(4-)
has participanthydron
has participantNADP(3-)
Subset
None
Related
Linkto allgenes and gene products annotated to aldose reductase (NADPH) activity (excluding "regulates").
Linkto all direct and indirectannotationsto aldose reductase (NADPH) activity (excluding "regulates").
Linkto all direct and indirectannotations download (limited to first 10,000)for aldose reductase (NADPH) activity (excluding "regulates").
Include "regulates"
For more information, please see theontology relation documentation.

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Graph of GO:0004032 from QuickGO

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Parents of aldose reductase (NADPH) activity (GO:0004032)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
aldose reductase (NADPH) activity[is_a relation] is_a alcohol dehydrogenase (NADP+) activity (GO:0008106)
aldose reductase (NADPH) activity[RO:0000057 relation] RO:0000057 alditol (CHEBI:17522)
aldose reductase (NADPH) activity[RO:0000057 relation] RO:0000057 aldose (CHEBI:15693)
aldose reductase (NADPH) activity[RO:0000057 relation] RO:0000057 NADPH(4-) (CHEBI:57783)
aldose reductase (NADPH) activity[RO:0000057 relation] RO:0000057 hydron (CHEBI:15378)
aldose reductase (NADPH) activity[RO:0000057 relation] RO:0000057 NADP(3-) (CHEBI:58349)
Children of aldose reductase (NADPH) activity (GO:0004032)
subject[Reorder by subject]relation[Reorder by relation]object[Reorder by object]
L-arabinose reductase (NADPH) activity (GO:0032867)[is_a relation] is_a  aldose reductase (NADPH) activity
D-xylose reductase (NADPH) activity (GO:0032866)[is_a relation] is_a  aldose reductase (NADPH) activity
EC
1.1.1.21
KEGG_REACTION
R02820
MetaCyc
ALDEHYDE-REDUCTASE-RXN
Reactome
R-HSA-5652172
R-HSA-196060
RHEA
12789
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