Developing transformative therapies.
Our company
At 35Pharma, we are dedicated to designing and developing best-in-class ligand traps that target Activin x GDF biology and address diseases with high unmet medical need including pulmonary hypertension, heart failure and obesity.
Leveraging decades of experience designing and developing ligand traps, our unique therapeutic modality enables tailored multi-specificity and potency, making ligand traps that are ideally suited to target the Activin x GDF signaling pathway.
Core to our scientific pursuit lies our experienced team with a proven track record of advancing complex biologics from discovery through clinical validation.
Activins and GDFs have been established as causal drivers of multiple diseases through genetic, translational and clinical evidence. These diseases include pulmonary hypertension, heart failure and obesity.
Utilizing breakthrough protein engineering, we designed multi-specific traps that are highly selective and potent. The beneficial properties of our next-generation traps far exceed those of older generation traps.
We execute biomarker-informed clinical trials that achieve rapid clinical proof-of-principle and accelerate time to market.
Our ligand traps are conveniently administered by infrequent subcutaneous injection.
HS235
HS235, our lead candidate, is in clinical development for Cardiometabolic disease and Pulmonary Hypertension.
HS235 was designed to improve pulmonary and cardiac function while simultaneously ameliorating metabolic health. This unique approach addresses the high unmet medical needs in pulmonary hypertension, heart failure and obesity.
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35Pharma is a biopharmaceutical company focused on designing and developing innovative biologics for diseases with high unmet medical need.
Montreal, QC H2Y 2Z4
Canada
50 Milk St.,
Boston, MA 02109
United States
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