In February 1967, he started working withDudley Herschbach atHarvard University on reactions betweenhydrogen atoms and diatomicalkali molecules and the construction of a universal crossed molecular beams apparatus. After the postdoctoral year with Herschbach he joined theUniversity of Chicago faculty in 1968. In 1974, he returned to Berkeley as professor of chemistry and principal investigator at theLawrence Berkeley National Laboratory, becoming a U.S. citizen the same year. Lee is a University Professor Emeritus of theUniversity of California system.[7]
One of the major goals ofchemistry is the study of material transformations wherechemical kinetics plays an important role. Scientists during the 19th century stated macroscopic chemical processes consist of many elementary chemical reactions that are themselves simply a series of encounters betweenatomic ormolecular species. In order to understand the time dependence ofchemical reactions,chemical kineticists have traditionally focused on sorting out all of the elementary chemical reactions involved in a macroscopic chemical process and determining their respective rates.
Other scientists at the time also stated a chemical reaction is fundamentally amechanical event, involving the rearrangement of atoms and moleculesduring acollision. Although these initial theoretical studies were only qualitative, they heralded a new era in the field of chemical kinetics; allowing the prediction of the dynamical course of a chemical reaction.
In the 1950s, 1960s and 1970s, with the development of many sophisticated experimental techniques, it became possible to study the dynamics of elementary chemical reactions in the laboratory. Such as the analysis of the threshold operating conditions of a chemicallaser or thespectra obtained using various linear or non-linear laser spectroscopic techniques.
Professor Lee's research focused on the possibility to control the energies of the reagents, and to understand the dependence of chemical reactivity on molecular orientation, among other studies related to the nature of reaction intermediates,decay dynamics, and identifying complexreaction mechanisms. To do so, Professor Lee used a breakthroughlaboratory technique at the time, called the"crossed molecular beams technique", where the information derived from the measurements of angular and velocity distributions allowed him and his team to understand the dynamics of elementary chemical reactions.[8]
During his tenure, Lee has worked to create new research institutes, advance scientific research within Taiwan, and to recruit and cultivate top scholars for theAcademia Sinica.
In 2010, Lee said that global warming would be much more serious than scientists previously thought, and that Taiwanese people needed to cut their per-capita carbon emissions from the current 12 tons per year to just three. This would take more than a few slogans, turning off the lights for one hour, or cutting meat consumption, noting: "We will have to learn to live the simple lives of our ancestors." Without such efforts, he said, "Taiwanese will be unable to survive long into the future".[10]
In July 2024, Lee accepted presidentLai Ching-te's invitation to serve as a consultant on the newly formed National Climate Change Strategy Committee.[14]
Lee was then elected President of theInternational Council for Science in 2008 and started his term in 2011.[15] He has been involved with the Malta Conferences, an initiative designed to bring together Middle Eastern scientists. As part of the initiative, he offered six fellowships to work on the synchrotron in Taiwan.[16] He is also a member of International Advisory Council inUniversiti Tunku Abdul Rahman.[17]
Lee (upper far left) represented Taiwan at the 2004APEC leaders' summit.
Lee's father was a painter in Taiwan, and his mother was an elementary school teacher. His elder brotherYuan-Chuan Lee has been a professor atJohns Hopkins University for 40 years and was awarded the honor Special Chair Lectureship in Academia Sinica in Taiwan. His younger brotherYuan-Pern Lee was also awarded this honor. Lee's sister Chi-Mei Lee has served as a professor atNational Chung Hsing University.[18]
In January 2004, he and industrial tycoonWang Yung-ching and theatre directorLin Hwai-min issued a joint statement to both Chen Shui-bian andLien Chan. He backed Chen again in the2004 elections, issuing a statement of support for the DPP on 17 March, three days before polls opened.