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Pogosta disease

From Wikipedia, the free encyclopedia
Medical condition
Pogosta disease
Other namesKarelian fever, Ockelbo disease
SpecialtyInfectious disease

Pogosta disease is aviral disease.[1][2] The symptoms of the disease usually includerash, as well as mildfever and otherflu-like symptoms; in most cases the symptoms last less than 5 days. However, in some cases, the patients develop a painfularthritis. There are no known chemical agents available to treat the disease.[3]

Signs and symptoms

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Cause

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It has long been suspected that the disease is caused by aSindbis-like virus, a positive-strandedRNA virus belonging to theAlphavirus genus and familyTogaviridae.[1] In 2002 a strain of Sindbis was isolated from patients during an outbreak of the Pogosta disease inFinland, confirming the hypothesis.[3]

Treatment

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There is currently no treatment available.

Epidemiology

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This disease is mainly found in the Eastern parts ofFinland; the disease was first detected in 1974 in the old parish village ofIlomantsi, sometimes calledPogosta.[4] A typical Pogosta disease patient is a middle-aged person who has been infected through amosquito bite while picking berries in the autumn. The prevalence of the disease is about 100 diagnosed cases every year, with larger outbreaks occurring in 7-year intervals.[3]

Etymology

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It is also known as Karelian fever and Ockelbo disease. The names are derived from the wordsPogosta,Karelia andOckelbo.[citation needed]

References

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  1. ^abLvov, D. K.; Vladimirtseva, E. A.; Butenko, A. M.; Karabatsos, N.; Trent, D. W.;Calisher, C. H. (1988). "Identity of Karelian fever and Ockelbo viruses determined by serum dilution-plaque reduction neutralization tests and oligonucleotide mapping".The American Journal of Tropical Medicine and Hygiene.39 (6):607–610.doi:10.4269/ajtmh.1988.39.607.PMID 2849885.
  2. ^Laine, Maria (2002).Pogosta Disease. University of Turku.ISBN 951-29-2129-4.
  3. ^abcKurkela S, Manni T, Vaheri A, Vapalahti O (May 2004)."Causative agent of Pogosta disease isolated from blood and skin lesions".Emerg Infect Dis.10 (5):889–894.doi:10.3201/eid1005.030689.PMC 3323234.PMID 15200824.
  4. ^Virus unique to Finland sees biggest outbreak in decadesYle News

External links

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Classification
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