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| Formula | C15H11ClN2 |
| Molar mass | 254.72 g·mol−1 |
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PS75 is an experimentalanalgesic drug which acts as afunctionally selectivealpha-2A (α2A) adrenergicagonist, with a Ki of 8.2nM and an EC50 of 4.8nM at the α2A-adrenergic receptor. In animal studies it was found to produce analgesia but without thesedation typical of older drugs acting at this target such asdexmedetomidine. While PS75 itself is unlikely to be developed for medical use, the successful separation of analgesia from sedative effects makes it likely that related compounds may be developed as non-sedating, non-opioid analgesic medications.[1]
