Mantle zone
Histology of a normal secondarylymphoid follicle, with yellow arrows pointing at the mantle zone.
Anatomical terminology [edit on Wikidata]

Themantle zone (or justmantle) of alymphatic nodule (orlymphatic follicle) is an outer ring of small lymphocytes surrounding agerminal center.^[1]

It is also known as the "corona".^[2]

It contains transientlymphocytes.^[3]

It is the location of thelymphoma inmantle cell lymphoma.

Mantle zone expansion may be seen in benign, such asCastleman disease, and malignancy,i.e.,Mantle cell lymphoma.Tcl-1 is expressed in the mantle zone.

• https://web.archive.org/web/20080813003821/http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
• Histology image: 07102loa – Histology Learning System at Boston University — "Lymphoid Tissues and Organs: lymph node, cortex and medulla"

• Lymphatic organ anatomy

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