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Lanthanum carbonate

From Wikipedia, the free encyclopedia
Ore of lanthanum metal
Lanthanum carbonate
Names
IUPAC name
Lanthanum carbonate
Other names
Fosrenol
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard100.008.728Edit this at Wikidata
EC Number
  • 209-599-5
KEGG
UNII
  • InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 checkY
    Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H checkY
  • InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
    Key: NZPIUJUFIFZSPW-CYFPFDDLAT
  • [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O
Properties
La2(CO3)3
Molar mass457.838 g/mol
AppearanceWhite powder, hygroscopic
Density2.6–2.7 g/cm3
Melting pointdecomposes
negligible
Solubilitysoluble in acids
Pharmacology
V03AE03 (WHO)
Legal status
Related compounds
Otheranions
Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Lanthanum carbonate,La2(CO3)3, is thesalt formed bylanthanum(III)cations andcarbonateanions. It is an ore oflanthanum metal (bastnäsite), along withmonazite.

Chemistry

[edit]

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Medical uses

[edit]

Lanthanum carbonate is used inmedicine as aphosphate binder.[1] As a medication it is sold under the trade nameFosrenol by the pharmaceutical companyShire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It isprescribed for the treatment ofhyperphosphatemia, primarily in patients withchronic kidney disease. It is taken with meals and binds to dietaryphosphate, preventing phosphate from being absorbed by theintestine. For cats withhyperphosphatemia it is available under the trade nameRenalzin byBayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namelymyalgia, muscular cramping, andperipheral edema, should be clinically monitored.[3]

Other applications

[edit]

Lanthanum carbonate is also used for the tinting of glass,[citation needed] for water treatment, and as acatalyst forhydrocarbon cracking.

References

[edit]
  1. ^Editorial Staff (December 2004)."Lanthanum Carbonate".All Micromedex Systems. Micromedex, Inc. Archived fromthe original on 2007-09-14. Retrieved2007-11-25.
  2. ^Bayer Animal Health (26 September 2008)."Bayer Animal Health launches Renalzin for Cats"(PDF). Archived fromthe original(PDF) on 7 July 2011. Retrieved2008-09-30.
  3. ^Tonelli, Marcello; Pannu, Neesh; Manns, Braden (2010). "Oral Phosphate Binders in Patients with Kidney Failure".New England Journal of Medicine.362 (14):1312–24.doi:10.1056/NEJMra0912522.PMID 20375408.S2CID 22322676.

External links

[edit]
Lanthanum compounds
Compounds containing thecarbonate group
Drugs for treatment ofhyperkalemia andhyperphosphatemia (V03AE)
Potassium binders
Phosphate binders
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