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LabKey Server

From Wikipedia, the free encyclopedia
Software suite
LabKey Server
Developer(s)LabKey
Stable release
21.3 / March 2021; 4 years ago (2021-03)[1]
Written inJava
Operating systemCross-platform
LicenseApache License 2.0
Websitewww.labkey.com

LabKey Server is a software suite available for scientists tointegrate,analyze, andshare biomedical research data. The platform provides a securedata repository that allows web-based querying, reporting, and collaborating across a range of data sources. Specific scientific applications and workflows can be added on top of the basic platform and leverage a data processingpipeline.

License

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LabKey licenses LabKey Server and its documentation for free under theApache License.[2]

Languages and extensibility

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The base platform is written inJava. It can be extended through the addition of Java-based modules or simple, file-based modules written inHTML,XML andJavaScript.[3] The platform can also be extended using LabKey Server'sJava,JavaScript,R,Python,Perl andSAS client libraries.[4]

History

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LabKey Server, originally known as the Computational Proteomics Analysis System (CPAS), was developed at theFred Hutchinson Cancer Research Center to manage high volumes of data generated at the Fred Hutch Computational Proteomics Lab. In 2005, a small team spun out of the Hutch and began operating independently as LabKey Software after contributors realized that the software could be beneficial to the broader scientific community.[5][6][7]

Core Components

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LabKey Server provides a secure data repository for all types of biomedical data, includingmass spectrometry,flow cytometry,microarray,microplate,ELISpot,ELISA,NAb andobservational study information. A customizable data processing pipeline allows the upload and processing of the large data files common in biomedical research.

The platform also provides domain-specific support for several areas of research, including:

  • Observational Studies. Supports management oflongitudinal, large-scale studies of participants, subjects or animals over time. Allows the integration of clinical data with assay results.
  • Proteomics. Allows the processing of high-throughput mass spectrometry data using tools such as theX! Tandem search engine, theTrans-Proteomic Pipeline,Mascot andSequest. Certified as "Silver-Level Compliant Data Service" with thecaBIG standard.
  • Flow Cytometry. Supports automated quality control, centralized data management and web-based data sharing. Integrates withFlowJo.

Zika Open Research Portal

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In 2016, LabKey and Professor Dave O'Connor of theUniversity of Wisconsin–Madison launched the Zika Open Research Portal[1] using LabKey Server. The portal provides direct access to experiment data being produced by members of the Zika Experimental Science Team (ZEST). The portal received attention from the scientific community for being the first platform of its kind to share real-time research data.[8][9]

Open Source Software

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Labkey is licensed in a variety of manners. Source-code is provided for a core set of features with the Community Edition, and there are also Premium Editions available.[10]

Users

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Users range from individual labs to large research consortia. In 2017, the program's users included the following:[11]

Publications

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References

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  1. ^"Release Notes 21.3 (March 2021): /Documentation".labkey.org. Retrieved2021-04-13.
  2. ^"LabKey Frequently Asked Questions: /home". Labkey.org. Retrieved2010-05-29.
  3. ^"Building Modules: /home/Documentation". Labkey.org. Retrieved2010-05-29.
  4. ^"LabKey API: /Documentation". Labkey.org. Retrieved2010-05-29.
  5. ^"Computational Proteomics Laboratory". Proteomics.fhcrc.org. Archived fromthe original on 2010-06-16. Retrieved2010-05-29.
  6. ^Wizards computational science.
  7. ^"Center News - 1/5/06 - Center, NCI launch open-source software for proteomics analysis". Fhcrc.org. 2006-01-05. Retrieved2010-05-29.
  8. ^Butler, Declan (2016-02-23)."Zika researchers release real-time data on viral infection study in monkeys".Nature. Nature News.doi:10.1038/nature.2016.19438.S2CID 168146966. Retrieved2016-02-23.
  9. ^"Zika Data From the Lab, and Right to the Web".New York Times. 2016-07-18. Retrieved2016-07-18.
  10. ^"LabKey Server - Research's Most Flexible Software Platform for Insight".
  11. ^"Our Clients | LabKey Software". Labkey.com. Retrieved2010-05-29.

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