Gap junction alpha-4 protein, also known asConnexin-37 orCx37, is aprotein that in humans is encoded by theGJA4gene.[5][6][7] This protein, like otherConnexin proteins, forms connections between cells known asgap junctions. Connexin 37 can be found in many tissues including theovary,[8]heart,[9] andkidney.[10]
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^Richard G, Smith LE, Bailey RA, Itin P, Hohl D, Epstein EH, DiGiovanna JJ, Compton JG, Bale SJ (December 1998). "Mutations in the human connexin gene GJB3 cause erythrokeratodermia variabilis".Nature Genetics.20 (4):366–9.doi:10.1038/3840.PMID9843209.S2CID841727.
Beyer EC, Paul DL, Goodenough DA (July 1990). "Connexin family of gap junction proteins".The Journal of Membrane Biology.116 (3):187–94.doi:10.1007/BF01868459.PMID2167375.S2CID43264684.
Willecke K, Jungbluth S, Dahl E, Hennemann H, Heynkes R, Grzeschik KH (December 1990). "Six genes of the human connexin gene family coding for gap junctional proteins are assigned to four different human chromosomes".European Journal of Cell Biology.53 (2):275–80.PMID1964417.
Van Camp G, Coucke P, Speleman F, Van Roy N, Beyer EC, Oostra BA, Willems PJ (November 1995). "The gene for human gap junction protein connexin37 (GJA4) maps to chromosome 1p35.1, in the vicinity of D1S195".Genomics.30 (2):402–3.PMID8586454.
van Rijen HV, van Kempen MJ, Postma S, Jongsma HJ (April 1998). "Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells".Cytokine.10 (4):258–64.doi:10.1006/cyto.1997.0287.PMID9617570.
Seul KH, Kang KY, Lee KS, Kim SH, Beyer EC (July 2004). "Adenoviral delivery of human connexin37 induces endothelial cell death through apoptosis".Biochemical and Biophysical Research Communications.319 (4):1144–51.doi:10.1016/j.bbrc.2004.05.097.PMID15194487.
