Blind pouch
From the posterior wall of thesaccule a canal, theendolymphatic duct , is given off; this duct is joined by theutriculosaccular duct , and then passes along thevestibular aqueduct and ends in a blind pouch, theendolymphatic sac , on the posterior surface of thepetrous portion of thetemporal bone , where it is in contact with thedura mater . Studies suggest that the endolymphatic duct and endolymphatic sac perform both absorptive andsecretory ,[ 1] [ 2] [ 3] [ 4] [ 5] [ 6] contrast agent uptake in the endolymphatic sac and duct inMRI is inversely correlated toendolymphatic hydrops ,[ 7] Meniere's Disease .[ 8]
Neoplasms of the endolymphatic sac are very rare tumors.
This article incorporates text in thepublic domain frompage 1052 of the 20th edition of Gray's Anatomy (1918)
^ Schuknecht HF. Pathology of the Ear. Philadelphia, Pa: Lea & Febiger; 1993:45–47, 50–51, 62, 64, 101 ^ Wackym, P. A.; Friberg, U.; Bagger-Sjöbäck, D.; Linthicum, F. H.; Friedmann, I.; Rask-Andersen, H. (August 1987)."Human endolymphatic sac: possible mechanisms of pressure regulation" .The Journal of Laryngology and Otology .101 (8):768– 779.doi :10.1017/s0022215100102713 .ISSN 0022-2151 .PMID 3655528 . ^ Yeo, S. W.; Gottschlich, S.; Harris, J. P.; Keithley, E. M. (June 1995)."Antigen diffusion from the perilymphatic space of the cochlea" .The Laryngoscope .105 (6):623– 628.doi :10.1288/00005537-199506000-00012 .ISSN 0023-852X .PMID 7769947 . ^ Rask-Andersen, H.; Danckwardt-Lillieström, N.; Linthicum, F. H.; House, W. F. (February 1991)."Ultrastructural evidence of a merocrine secretion in the human endolymphatic sac" .The Annals of Otology, Rhinology, and Laryngology .100 (2):148– 156.doi :10.1177/000348949110000211 .ISSN 0003-4894 .PMID 1992902 . ^ Fukazawa, K.; Sakagami, M.; Matsunaga, T.; Fujita, H. (July 1991)."Endocytotic activity of the free floating cells and epithelial cells in the endolymphatic sac: an electron microscopic study" .The Anatomical Record .230 (3):425– 433.doi :10.1002/ar.1092300315 .ISSN 0003-276X .PMID 1867416 . ^ Wackym, P. A.; Friberg, U.; Linthicum, F. H.; Bagger-Sjöbäck, D.; Bui, H. T.; Hofman, F.; Rask-Andersen, H. (May–June 1987)."Human endolymphatic sac: morphologic evidence of immunologic function" .The Annals of Otology, Rhinology, and Laryngology .96 (3 Pt 1):276– 281.doi :10.1177/000348948709600308 .ISSN 0003-4894 .PMID 3300505 . ^ J. Gerb, E. Kierig, V. Kirsch, Sandra Becker‐Bense, Rainer Boegle, Thomas Brandt, Marianne Dieterich:Contrast Agent Uptake in Endolymphatic Sac and Duct: Inverse Relation to Endolymphatic Hydrops. In:The Laryngoscope. 2025doi :10.1002/lary.32127 . ^ David Bächinger, Ngoc-Nhi Luu, Judith Kempfle, Samuel R. Barber, Daniel Zürrer, Daniel J. Lee, Hugh D. Curtin, Steven D. Rauch, Joseph B. Nadol, Joe C. Adams, Andreas H. Eckhard:Vestibular Aqueduct Morphology Correlates With Endolymphatic Sac Pathologies in Menière's Disease—A Correlative Histology and Computed Tomography Study. In:Otology & Neurotology. 2019, Band 40, Nummer 5, S. e548–e555doi :10.1097/MAO.0000000000002198 .
This article incorporates text in thepublic domain frompage 1052 of the 20th edition ofGray's Anatomy(1918)
