Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

EA-2192

From Wikipedia, the free encyclopedia
EA-2192
Names
Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate
Other names
Diisopropylaminoethyl methyl thiolophosphonate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • CC(C)N(CCSP(=O)(C)O)C(C)C
Properties
C9H22NO2PS
Molar mass239.31 g·mol−1
AppearanceWhite solid
Very soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
Extremely toxic
Lethal dose or concentration (LD, LC):
630 μg/kg (Rat, oral)
18 μg/kg (Rat, iv)
50 μg/kg (Mouse, iv)
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

EA-2192 is an extremely toxic degradation product of theVX, a very potentnerve agent.[1][2] It is a white solid that is very soluble and stable in water.

EA-2192 is an extremely potentacetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]

EA-2192 behaves similar to agedsoman as it is thedealkylated form of VX and cannot be reversed with commonoxime reactivators.

EA-2192 from VX

See also

[edit]

References

[edit]
  1. ^Ellison, D. Hank (2007).Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC.ISBN 9780849314346.
  2. ^Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer,ISBN 978-0-387-34626-7
  3. ^Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999)."The sources, fate, and toxicity of chemical warfare agent degradation products".Environmental Health Perspectives.107 (12):933–74.doi:10.1289/ehp.99107933.PMC 1566810.PMID 10585900.
Blood agents
Blister agents
Arsenicals
Sulfur mustards
Nitrogen mustards
Nettle agents
Other
Nerve agents
G-agents
V-agents
GV agents
Novichok agents
Carbamates
Other
Precursors
Neurotoxins
Pulmonary/
choking agents
Vomiting agents
Incapacitating
agents
Lachrymatory
agents
Malodorant agents
Cornea-clouding agents
Biological toxins
Tumor promoting agents
Other
Animal toxins
Bacterial
Cyanotoxins
Plant toxins
Mycotoxins
Pesticides
Nerve agents
Bicyclic phosphates
Cholinergic neurotoxins
Psychoactive drugs
Other
Enzyme
(modulators)
ChATTooltip Choline acetyltransferase
AChETooltip Acetylcholinesterase
BChETooltip Butyrylcholinesterase
Transporter
(modulators)
CHTTooltip Choline transporter
VAChTTooltip Vesicular acetylcholine transporter
Release
(modulators)
Inhibitors
Enhancers
Stub icon

This article about anorganic compound is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=EA-2192&oldid=1263318279"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp