Achloride channel blocker is a type ofdrug which inhibits the transmission ofions (Cl−) throughchloride channels.
Niflumic acid is a chloride channel blocker that has been used in experimentalscientific research.[1] Another example isanthracene-9-carboxylic acid, a potent blocker of theCLCN1-type chloride channel found in skeletal muscle, which is used to study animal models ofmyotonia congenita.[2]
Some antagonists ofglycine receptors andGABAA receptors also act as chloride channel blockers.
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