Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Chloride channel blocker

From Wikipedia, the free encyclopedia

Achloride channel blocker is a type ofdrug which inhibits the transmission ofions (Cl) throughchloride channels.

Niflumic acid is a chloride channel blocker that has been used in experimentalscientific research.[1] Another example isanthracene-9-carboxylic acid, a potent blocker of theCLCN1-type chloride channel found in skeletal muscle, which is used to study animal models ofmyotonia congenita.[2]

Some antagonists ofglycine receptors andGABAA receptors also act as chloride channel blockers.

See also

[edit]

References

[edit]
  1. ^Knauf PA, Mann NA (May 1984)."Use of niflumic acid to determine the nature of the asymmetry of the human erythrocyte anion exchange system".The Journal of General Physiology.83 (5):703–25.doi:10.1085/jgp.83.5.703.PMC 2215658.PMID 6736917.
  2. ^Villegas-Navarro A, Martinez-Morales M, Morales-Aguilera A (March 1986). "Pharmacokinetics of anthracene-9-carboxylic acid, a potent myotonia-inducer".Archives Internationales de Pharmacodynamie et de Thérapie.280 (1):5–21.PMID 3718080.

Further reading

[edit]
Types
Classes
Enzyme
Ion channel
Receptor &
transporter
BA/M
Adrenergic
Dopaminergic
Histaminergic
Serotonergic
AA
GABAergic
Glutamatergic
Cholinergic
Cannabinoidergic
Opioidergic
Other
Miscellaneous
Calcium
VDCCsTooltip Voltage-dependent calcium channels
Blockers
Activators
Potassium
VGKCsTooltip Voltage-gated potassium channels
Blockers
Activators
IRKsTooltip Inwardly rectifying potassium channel
Blockers
Activators
KCaTooltip Calcium-activated potassium channel
Blockers
Activators
K2PsTooltip Tandem pore domain potassium channel
Blockers
Activators
Sodium
VGSCsTooltip Voltage-gated sodium channels
Blockers
Activators
ENaCTooltip Epithelial sodium channel
Blockers
Activators
ASICsTooltip Acid-sensing ion channel
Blockers
Chloride
CaCCsTooltip Calcium-activated chloride channel
Blockers
Activators
CFTRTooltip Cystic fibrosis transmembrane conductance regulator
Blockers
Activators
Unsorted
Blockers
Others
TRPsTooltip Transient receptor potential channels
LGICsTooltip Ligand gated ion channels


Stub icon

Thispharmacology-related article is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Chloride_channel_blocker&oldid=1264643638"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp