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Carbosulfan

From Wikipedia, the free encyclopedia
Carbosulfan
Names
IUPAC name
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl [(dibutylamino)sulfanyl]methylcarbamate
Other names
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl[(dibutylamino)thio] methylcarbamate
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
ECHA InfoCard100.054.132Edit this at Wikidata
UNII
  • InChI=1S/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3 checkY
    Key: JLQUFIHWVLZVTJ-UHFFFAOYSA-N checkY
  • InChI=1/C20H32N2O3S/c1-6-8-13-22(14-9-7-2)26-21(5)19(23)24-17-12-10-11-16-15-20(3,4)25-18(16)17/h10-12H,6-9,13-15H2,1-5H3
    Key: JLQUFIHWVLZVTJ-UHFFFAOYAN
  • O=C(Oc2cccc1c2OC(C1)(C)C)N(SN(CCCC)CCCC)C
Properties
C20H32N2O3S
Molar mass380.55 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Carbosulfan is anorganic compound adherent to thecarbamate class. At normal conditions, it is brownviscousliquid. It is not very stable; itdecomposes slowly atroom temperature. Itssolubility inwater is low but it ismiscible withxylene,hexane,chloroform,dichloromethane,methanol andacetone. Carbosulfan is used as aninsecticide.[1] TheEuropean Union banned use of carbosulfan in 2007.[2]

Its oralLD50 forrats is 90 to 250 mg/kgbw, inhalation LC50 is 0.61 mg/L. Carbosulfan is only slightly absorbed throughskin (LD50 >2000 mg/kg forrabbits). The mechanism oftoxicity is based on reversibleinhibition ofacetylcholinesterase (as for carbamates generally).[3]Carbosulfan has very low maximum residue limits for use in the EU and UK examples of this can be seen in apples and oranges, where it is 0.05 mg/kg.

See also

[edit]

References

[edit]
  1. ^CARBOSULFAN – Pesticide residues in food – 1984
  2. ^COMMISSION DECISION of 13 June 2007 concerning the non-inclusion of carbosulfan in Annex I to Council Directive 91/414/EEC and the withdrawal of authorisations for plant protection products containing that substance
  3. ^CARBOSULFAN – Pesticide residues in food – 2003


Carbamates
Inorganic compounds
Insect growth regulators
Neonicotinoids
Organochlorides
Organophosphorus
Pyrethroids
Diamides
Other chemicals
Metabolites
Biopesticides
Enzyme
(modulators)
ChATTooltip Choline acetyltransferase
AChETooltip Acetylcholinesterase
BChETooltip Butyrylcholinesterase
Transporter
(modulators)
CHTTooltip Choline transporter
VAChTTooltip Vesicular acetylcholine transporter
Release
(modulators)
Inhibitors
Enhancers
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