Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

CAR-301,060

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
CAR-301,060
Identifiers
  • [(7R,8R)-7-methyl-1-azabicyclo[2.2.2]octan-8-yl]2-cyclopentyl-2-hydroxy-2-phenylacetate
CAS Number
PubChemCID
ChemSpider
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC21H29NO3
Molar mass343.467 g·mol−1
3D model (JSmol)
  • C[C@@H]1[C@@H](C2CCN1CC2)OC(=O)C(C3CCCC3)(C4=CC=CC=C4)O
  • InChI=1S/C21H29NO3/c1-15-19(16-11-13-22(15)14-12-16)25-20(23)21(24,18-9-5-6-10-18)17-7-3-2-4-8-17/h2-4,7-8,15-16,18-19,24H,5-6,9-14H2,1H3/t15-,19+,21?/m1/s1
  • Key:ICYFZPARHUFDKQ-GAKLZJQJSA-N
  (verify)

CAR-301,060 (also known ascis-2-Methyl-3-quinuclidinylphenylcyclopentylglycolate or just by its code number301060) is a potent and long lastinganticholinergicdeliriant drug, related to thechemical warfare agent3-Quinuclidinyl benzilate (QNB). It was developed under contract toEdgewood Arsenal, Fort Detrick,Maryland during the 1960s as part of theUS military chemical weapons program, during research to improve upon the properties of earlier agents such as QNB.

CAR-301,060 was found to be slightly less potent than QNB, and with around the same duration of action, but with a very high central to peripheral effects ratio.[1][2]

See also

[edit]

References

[edit]
  1. ^National Research Council (US) Panel on Anticholinesterase Chemicals; National Research Council (US) Panel on Anticholinergic Chemicals (1982).Possible Long-Term Health Effects of Short-Term Exposure to Chemical Agents. Vol. 1. The National Academies Press. pp. 199–200.doi:10.17226/740.ISBN 978-0-309-07759-0.PMID 25032448.
  2. ^Ketchum JS (2006).Chemical Warfare Secrets Almost Forgotten. A Personal Story of Medical Testing of Army Volunteers with Incapacitating Chemical Agents During the Cold War. ChemBooks Inc.ISBN 978-1-4243-0080-8.
Psychedelics
(5-HT2AR agonists)
  • For a full list of serotonergic psychedelics, see the navboxhere instead.
Dissociatives
(NMDARantagonists)
Arylcyclo‐
hexylamines
Adamantanes
Diarylethylamines
Morphinans
Others
Deliriants
(mAChRantagonists)
Cannabinoids
(CB1R agonists)
Natural
Synthetic
AM-x
CPx
HU-x
JWH-x
Misc.
  •  For a full list of cannabinoids, see the navboxhere instead.
κORagonists
GABAARagonists
Inhalants
(mixedMoATooltip mechanism of action)
Others
mAChRsTooltip Muscarinic acetylcholine receptors
Agonists
Antagonists
Precursors
(andprodrugs)


Stub icon

Thishallucinogen-related article is astub. You can help Wikipedia byexpanding it.

Fort D

Retrieved from "https://en.wikipedia.org/w/index.php?title=CAR-301,060&oldid=1276172792"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp