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Benzomorphan

From Wikipedia, the free encyclopedia
Benzomorphan
Names
IUPAC name
6,7-Benzomorphan
Other names
  • 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine<
  • 10-Azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-triene
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2 ☒N
    Key: NSLKFRGZLUIUKO-UHFFFAOYSA-N ☒N
  • InChI=1/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2
    Key: NSLKFRGZLUIUKO-UHFFFAOYAF
  • C1CNC2CC1C3=CC=CC=C3C2
Properties
C12H15N
Molar mass173.259 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

Benzomorphan is achemical compound that is the base for a series ofdrugs which variably act on thesigma receptors andκ-opioid receptors, including the following compounds:

Some of these agents are used asanalgesics, includingpentazocine,phenazocine,dezocine, andeptazocine.[1][2]

See also

[edit]

References

[edit]
  1. ^Kar, Ashutosh (2005).Medicinal Chemistry - Google Books.ISBN 9788122415650.
  2. ^Cittern PA, Kapoor VK, Parfitt RT (October 1986). "Preparation and analgesic activity of (−)-11 alpha-substituted 1,2,3,4,5,6-hexahydro-6 alpha,7-(methyleneoxy)-2,6-methano-3-benzazocines".Journal of Medicinal Chemistry.29 (10):1929–33.doi:10.1021/jm00160a022.PMID 2876100.
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