Movatterモバイル変換


[0]ホーム

URL:


Jump to content
WikipediaThe Free Encyclopedia
Search

Acecarbromal

From Wikipedia, the free encyclopedia
Acecarbromal
Seletal formula of acebromal
Seletal formula of acebromal
Names
Preferred IUPAC name
N-(Acetylcarbamoyl)-2-bromo-2-ethylbutanamide
Other names
1-Acetyl-3-(2-bromo-2-ethylbutyryl)urea
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard100.000.953Edit this at Wikidata
EC Number
  • 201-047-1
KEGG
MeSHacecarbromal
UNII
  • InChI=1S/C9H15BrN2O3/c1-4-9(10,5-2)7(14)12-8(15)11-6(3)13/h4-5H2,1-3H3,(H2,11,12,13,14,15) checkY
    Key: SAZUGELZHZOXHB-UHFFFAOYSA-N checkY
  • CCC(Br)(CC)C(=O)NC(=O)NC(C)=O
Properties
C9H15BrN2O3
Molar mass279.134 g·mol−1
Pharmacology
Oral
Legal status
  • In general: ℞ (Prescription only)
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Acecarbromal (INN) (brand namesSedamyl,Abasin,Carbased,Paxarel,Sedacetyl, numerous others), also known asacetylcarbromal andacetyladalin, is ahypnotic andsedativedrug of theureide (acylurea) group discovered byBayer in 1917[1] that was formerly marketed in theUnited States andEurope.[2][3] It is also used in combination with extract ofquebracho andvitamin E as a treatment forerectile dysfunction under the brand nameAfrodor in Europe.[4][5][6] Acecarbromal is structurally related to thebarbiturates, which are basically cyclizedureas.[7] Prolonged use is not recommended as it can causebromine poisoning.[7]

See also

[edit]

References

[edit]
  1. ^DE 327129, "Verfahren zur Darstellung von Derivaten bromacylierter Harnstoffe (Procedures for the preparation of derivatives of bromoacylated urea)", issued 5 October 1920, assigned to Bayer AG 
  2. ^Elks J (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 2–.ISBN 978-1-4757-2085-3.
  3. ^Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 4–.ISBN 978-3-88763-075-1.
  4. ^Muller NF, Dessing RP, eds. (19 June 1998).European Drug Index: European Drug Registrations, Fourth Edition. CRC Press. pp. 36–.ISBN 978-3-7692-2114-5.
  5. ^Baumbusch F, Papp GK, Kopa ZS (1995). "Treatment for potency problems with Afrodor 2000".Acta Chirurgica Hungarica.35 (1–2):87–92.PMID 8659243.
  6. ^Sperling H, Lümmen G, Luboldt HJ, Rübben H (January 1999). "[Secondary erectile dysfunction. Is oral medication in the diagnostic phase indicated?]".Der Urologe. Ausg. A.38 (1):56–9.doi:10.1007/s001200050246.PMID 10081103.S2CID 24907635.
  7. ^abWilliams DA, Foye WO, Lemke TL (January 2002).Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 380–.ISBN 978-0-683-30737-5.
GABAA
Alcohols
Barbiturates
Benzodiazepines
Carbamates
Imidazoles
Monoureides
Neuroactive steroids
Nonbenzodiazepines
Phenols
Piperidinediones
Quinazolinones
Others
GABAB
H1
Antihistamines
Antidepressants
Antipsychotics
α2-Adrenergic
5-HT2A
Antidepressants
Antipsychotics
Others
Melatonin
Orexin
α2δVDCC
Others
Forerectile dysfunction
Prostaglandins (E)
PDE5 inhibitors
Alpha blockers
Dopamine agonists
Melanocortin agonists
Others
Forpremature ejaculation
SSRIs
Oxytocin antagonists
DRA/DRIs
Alcohols
Barbiturates
Benzodiazepines
Carbamates
Flavonoids
Imidazoles
Kava constituents
Monoureides
Neuroactive steroids
Nonbenzodiazepines
Phenols
Piperidinediones
Pyrazolopyridines
Quinazolinones
Volatiles/gases
Others/unsorted
Stub icon

Thissedative-related article is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=Acecarbromal&oldid=1190968520"
Categories:
Hidden categories:

[8]ページ先頭

©2009-2025 Movatter.jp