5,N,N-trimethyltryptamine (5,N,N-TMT;5-TMT) is atryptaminederivative that is apsychedelic drug. It was first made in 1958 by Edwin H. P. Young.[1] In animal experiments it was found to be in betweenDMT and5-MeO-DMT in potency[2][3] which would suggest an active dosage for humans in the 20–60 mg range. Human psychoactivity for this compound has been claimed in reports on websites such asErowid but has not been independently confirmed.[medical citation needed]
5,N,N-TMT is not scheduled at the federal level in theUnited States,[4][5] but it could be considered an analog of5-MeO-DMT, in which case, sales or possession intended for human consumption could be prosecuted under theFederal Analog Act.
^Young EH (1958). "704. The synthesis of 5-hydroxytryptamine (serotonin) and related tryptamines".Journal of the Chemical Society (Resumed):3493–6.doi:10.1039/JR9580003493.
^Glennon RA, Gessner PK (April 1979). "Serotonin receptor binding affinities of tryptamine analogues".Journal of Medicinal Chemistry.22 (4):428–32.doi:10.1021/jm00190a014.PMID430481.
^Glennon RA, Young R, Rosecrans JA, Kallman MJ (1980). "Hallucinogenic agents as discriminative stimuli: a correlation with serotonin receptor affinities".Psychopharmacology.68 (2):155–8.doi:10.1007/BF00432133.PMID6776558.S2CID1674481.
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