therapeutic index

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Related to Therapeutic dose:Toxic Dose

therapeutic index

n.
The ratio between the toxic dose and the therapeutic dose of a drug, used as a measure of the relative safety of the drug for a particular treatment.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ther′apeu′tic in′dex



n.
the ratio between the dosage of a drug that causes a lethal effect and the dosage that causes a therapeutic effect.
[1925–30]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.


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References in periodicals archive?
We are excited to explore the extent of this drug's potential as we progress with dose escalation and approach the expected optimaltherapeutic dose of the drug.'
The FDA cleared assay is a non-invasive saliva test that identifies genetic signatures associated with patient metabolization of the drug Coumadin, which will assist doctors in adjusting a patient'stherapeutic dose to safer and more effective levels.
The APA Practice Guideline also states that although the highest "usualtherapeutic dose" for panic disorder is clonazepam 2 mg/d or alprazolam 4 mg/d, "higher doses are sometimes used for patients who do not respond to the usualtherapeutic dose." (1)
There was only a "trace of a nonnarcotic medicine in atherapeutic dose" in his system, reported the New York Times.
Animals (mice or rats) that have received atherapeutic dose of LD50 of a substance will be considered hypnotized if they lose their straightening reflexes when put on their backs.
PARIS--Of patients with major depressive disorder who receive a selective serotonin reuptake inhibitor (SSRI) or serotonin norepinephrine reuptake inhibitor (SNRI) as their initial pharmacotherapy, 40% do not achieve the minimumtherapeutic dose within 4 weeks of diagnosis, according to a real-world study of U.S.
This balm offers atherapeutic dose of menthol crystals and peppermint oils, with healing arnica and camphor, according to the company.
A variety of African plants are used for medicinal products, however, the difference between atherapeutic dose and a toxic one is often poorly understood.
Her medications included bumetanide, clonazepam, colchicine .6 mg BID, atherapeutic dose of cyclosporine, flurazepam, gabapentin, levothyroxine, mirtazapine, oxycodone, prednisone, and premarin.
Regarding the effect of atherapeutic dose of pseudoephedrine (PSE) on swimmers' performance:
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