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Purinergic Signalling

The Official Journal of the International Purine Club

Publishing model:
Hybrid

Overview

This journal presents a forum for the publication of papers in the rapidly growing area of Purinergic Signalling (through purines and pyrimidines), with its exceptionally wide spectrum of signalling functions in health and disease. Coverage includes original articles, reviews, hot topics and controversies, and meeting reports.

There is both short-term purinergic signalling in transmission and secretion and long-term (trophic) signalling in controlling cell proliferation, differentiation, motility and death in development and regeneration. At the molecular level, rapid progress has been made in understanding the mechanisms of nucleotide and nucleoside release, their extracellular metabolism, the intracellular signalling cascades elicited by receptor activation and the cross-talk with other essential signalling pathways. In addition to basic research into the roles of purines and pyrimidines in physiological conditions, a recent emphasis is on translational research and the therapeutic opportunities concerning purinergic signalling.

Editor-in-Chief
  • Charles Kennedy

Journal metrics

Journal Impact Factor
2.4 (2024)
5-year Journal Impact Factor
2.8 (2024)
Submission to first decision (median)
6 days
Downloads
298.3k (2024)

Calls for papers

Collection

Purinergic Signalling- A Perspective from China (III)

After two very successful special issues, we open for submissions the third edition of this collection.

Status
Open for submissions
Submission deadline
30 September 2026

Collection

A tribute to Francesco di Virgilio

We are organising a Special Issue in Purinergic Signalling in honour and in loving memory of Francesco di Virgilio, who died suddenly on September...

Status
Open for submissions
Submission deadline
30 June 2026

Collection

P2X receptors as therapeutic targets: a European perspective

P2X receptors (P2XRs) are ATP-gated ion channels involved in intercellular communication with an established role in neurodegeneration, infection,...

Status
Open for submissions
Submission deadline
31 December 2025

Latest articles

  1. Blockage of P2X7 receptor activation attenuated bone loss in ligature-induced model of periodontitis in rats

    • Nadine Linhares
    • Marco Aurelio Teófilo
    • Paula Goes
    Research 29 September 2025
  2. Breast cancer patients present pro-tumor biomarkers related to purinergic signaling and oxidative stress

    • Eduarda Valcarenghi Jabonski
    • Simone Luciana Triquez
    • Sarah Franco Vieira de Oliveira Maciel
    Methodology 02 September 2025
  3. Editorial: Purinergic signalling—a perspective from China (II)

    • Yong Tang
    • Peter Illes
    Correspondence 29 August 2025 Pages: 1009 - 1012
  4. The P2X7 receptor in leukemia: pathological mechanisms and therapeutic potential

    • Yanwen Xue
    • Xiaoxiang Peng
    • Ronglan Zhao
    Review 22 August 2025
  5. Astrocytes: crucial transducers that convert norepinephrine inputs to ATP signaling in the brain

    • Yuto Kubota
    • Eiji Shigetomi
    • Schuichi Koizumi
    Journal Club 19 August 2025

Journal updates

  • The Purine Club on LinkedIn

    Join in order to keep up with the latest developments in the field and to advertise your own publications, positions available and forthcoming conferences.

    https://www.linkedin.com/groups/1897873/

  • Tributes and memories to Professor Geoff Burnstock

    Obituary:Professor Dr. Geoffrey Burnstock (1929–2020)


    Professor Geoffrey Burnstock, a great luminary in science and the founder of our field of purinergic signalling, sadly died peacefully in Melbourne, Australia, on the 2nd of June, 2020, at the age of 91.Purinergic Signalling, the journal that he founded and led for so many years, are creating a page on its website that will be dedicated to your tributes to and memories of Geoff. Please share these by emailing them to Dr. Charles Kennedy, deputy Editor-in-Chief, Purinergic Signalling, atc.kennedy@strath.ac.uk by November 1st 2020.

  • Journal Club

    Purinergic Signalling has introduced a new type of article,Journal Club, that comprises a short review of recent, important papers in our field that have been published in other major scientific journals, such as Nature and Science. Please see thePDF file for details.

  • Call for Papers: A tribute to Francesco di Virgilio

    We are organising a Special Issue inPurinergic Signalling in honour and in loving memory of Francesco di Virgilio, who died suddenly on September 22nd 2024. Francesco was one of the giants of purinergic signalling and made many important contributions to the field. The guest editors invite submissions in the form of original contributions or reviews to this issue.

    Submission deadline: 30th June, 2026

Journal information

Electronic ISSN
1573-9546
Print ISSN
1573-9538
Abstracted and indexed in
  1. BIOSIS
  2. Baidu
  3. Biological Abstracts
  4. CLOCKSS
  5. CNKI
  6. CNPIEC
  7. Chemical Abstracts Service (CAS)
  8. Dimensions
  9. EBSCO
  10. EMBASE
  11. Google Scholar
  12. Japanese Science and Technology Agency (JST)
  13. Medline
  14. Meta
  15. Naver
  16. Norwegian Register for Scientific Journals and Series
  17. OCLC WorldCat Discovery Service
  18. Pathway Studio
  19. Portico
  20. ProQuest
  21. PubMedCentral
  22. Reaxys
  23. SCImago
  24. SCOPUS
  25. Science Citation Index Expanded (SCIE)
  26. TD Net Discovery Service
  27. Wanfang
  28. eLibrary.ru
© Springer Nature B.V.

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