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A
Hypothyroidism Ventricular septal defect
Multiple Drug SensitivityOccurs in 25.9 % of miniature Australian Shepherds, smaller persent of Australian Shepherds. MDR1 gene Problme drugs: Ivermectin, Loperamide, Doxorubicin, Vincristine, Vinblastine, Cyclosporin, Digoxin, Acepromazine, Butorphanol Potential Problem Drugs: Ondansetron, Domperidone, Paclitaxel, Mitoxantrone, Etoposide, Rifampicin, Quinidine, Morphine Test available:http://www.vetmed.wsu.edu/depts-VCPL/test.asp
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B
Hereditary factors not determined Defective formation of linea alba causing protrusion of abdominal contents through inguinal canal usually disappears by 12 weeks of age Intestinal malabsorption Lymphangiectasia Lymphocytic/plasmocytic enteritis Persistent pupillary membrane Progressive Retinal Atrophy Pyruvate kinase deficiencyshortened red blood cell life span Renal tubular dysfunction Umbilical hernia
AchondroplasiaForeleg lameness due to unusual anatomy Anomaly of third cervical vertebraeDeformed vertebral body resulting in pressure necrosis of overlying cord in coordination from birth to six months of age Atopy Ectropion Entropion Gastric torsion Immunodeficiency Inguinal herniaA condition considered high risk in this breed Hereditary factors not determined Defective formation of linea alba causing protrusion of abdominal contents through inguinal canal Interdigital inclusion cysts Lafara's diseaseSeizures retarded growth susceptibility to viral and bacterial infections Malasezia dermatitis Osteochondritis dissecansDefect or necrosis of articular cartilage in shoulder causing distinct favoring of affected limb Osteodystrophy Otitis externa Oversized palpebral fissure Patella luxationProposed recessive polygenic and multi-focal inheritance Medial or lateral Most common are medial Tiibial rotation on the long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age. Persistent pupillary membrane Platelet disorderMild to moderately severe bleeding Prolonged bleeding time Abnormal platelet aggregation and adhesiveness Poor clot retraction Primary glaucomaIncreased intraocular pressure Associated with lens luxation Progressive retinal degeneration Protrusion of the gland of the third eyelid Pulmonic Stenosis Seborrhea, primary Skin fold intertrigo Torsion of lung Ventricular Septal Defect
Chronic hepatitis deficiency Ventricular Septal Defect
Degenerative Valve Disease Patent Ductus Arteriosus
External ear infections, hematoma and moist dermatitis. Malocclusion Subaortic Stenosis
Sight is best in dim light affecting dogs 3-5 years of age. Ceroid liposuscinosisBehavioral changes Hyperactivity followed by aggression at 16-23 months. Motor abnormalities Blindness Corneal dystrophy Cryptorchidism. Dearness Osteochondritis dissecans Patent ductus arteriosusPersistence and non-closure of ductus arteriosus between aorta and pulmonary artery with left to right shunt.
Chemodectoma +/- pericardial effusion Degenerative Valve Disease Dilated Cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy Chemodectoma +/- pericardial effusion Arrhythmogenic right ventricular cardiomyopathy Boxer cardiomyopathy Histiocytoma histiocytes
Degenerative valve disease Pulmonic stenosis
deficiency Persistant right aortic arch
Hereditary abnormal dentitionPresence of one extra incisor Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to severe hip lameness. Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation and on the secondary degenerative joint disease HydrocephalusSeveral recessive genes Dilation of ventricles of brain with increased cerebrospinal fluid pressure. Hypoplasia of tracheaSmall, rigid cartilaginous rings with free ends in apposition Cough, abnormal respiratory sounds, dyspnea and decreased exercise tolerance in first 2 months of life. Cannot be surgically removed. Hypothyroidism Keratitis siccaDry cornea due to inefficient lacrimal secretion Mitral valve defects Muzzle pyodermaLocalized infectious dermatitis Oligodendroglioma Open urethra Oversize palpebral fissure Persistent pupillary membrane Predisposition to dystociaAnatomical peculiarities Fetal death or nervousness of the dam. Prolapsed male urethra Pulmonic stenosisNarrow pulmonary artery at its origin Pyloric stenosisHypertrophic obstruction of the pyloric office of the stomach Redundant forehead skin Reflex regurgitation Schistosomus reflexes Short skull Spina bifidaUnunited neural arches May result in herniation of meninges and/or cord (spina bifida manifesta) or may not (spina bifida occulta) Hemivertebra Asymetric , abnormal development of vertebrae which may result in neonatal death or cord compression in older puppies. Affected vertebrae become wedge-shaped due to underdevelopment of one half, resulting in scoliosis or kinked tails and crowding of ribs if in the thoracic area. Stenotic nares SwimmersCharacterized by inability to stand at 4-6 weeks of age and flattened chest. Vaginal hyperplasia Wrinkle dermatitis Wry mouth
Dilated Cardiomyopathy
Pulmonic Stenosis
Mitral valve dysplasia
Mitral valve stenosis
Subaortic stenosis
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C
Degenerative valve disease Epilepsy Inherited ventricular arrhythmias Mitral Valve Disease. Patent ductus arteriosus Retinal Dysplasia Right atrial hemangiosarcoma +/- pericardial effusion Syringomy secondary to occipital bone hypoplasiaaffected dogs could be traced back to one bitch born in 1956 and the two offspring from her single litter Unconfirmed suspicion is autosomal recessive inheritance. Occipital Bone Malformation, Hydrocephalus, Syrinx formations along the spine Symptoms: Scratching at head, neck or at nothing especially on a lead, screaming for no apparent reason. MRI required for diagnosis. Surgical correction
Degenerative valve disease Patent ductus arteriosus
Bowed forelegs Elbow dysplasia Entropion Food sensitivity Hiatal hernias Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to severe hip lameness Radiographically there may be shallow acetabulum Flattened femoral head Subluxation Secondary degenerative joint disease Idiopathic mucinosisPitting edema Alopecia Hyperpigmentation severe wrinkling of head and extremities Immunoglobulin A deficiency Inflammatory bowel disease Interdigital erythema and pruritisThickening, infections and hair loss due to skin folds Medial and lateral patellar luxationMedial or lateral Most common are medial Accompanied by tibial rotation on the long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age Otitis externaResult of ears close to head, irritation Photophobia and blepharospasm Stenotic nares Undershot jawAbnormal relative growth of the mandible
Adrenal sex hormone abnormalities Pulmonic stenosis Ventricular septal defect
Degenerative valve disease Dilated cardiomyopathy Pulmonic stenosis Sick sinus syndrome
Multiple Drug SensitivityMDR1 gene Problme drugs: Ivermectin, Loperamide, Doxorubicin, Vincristine, Vinblastine, Cyclosporin, Digoxin, Acepromazine, Butorphanol Potential Problem Drugs: Ondansetron, Domperidone, Paclitaxel, Mitoxantrone, Etoposide, Rifampicin, Quinidine, Morphine Test available:http://www.vetmed.wsu.edu/depts-VCPL/test.asp
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D
Acanthosis nigricans Cleft of lip and palateMedian fissures due to nonclosure of bones. Colonic perforation Color dilution alopecia Conjunctival dermoid Corneal dystrophyboth epithelial (superficial) and endothelial Corneal erosion (superficial) CystinuriaExcess cystine in urine. Predisposing to calculi. Deafness Degenerative valve disease Demodicosis Dermoid cysts Diabetes mellitus Ectasia of scleraExcessive tortuosity of retinal vessels. Chorioretinal dysplasia. Excavation of the optic disc. Retinal detachment. Intraocular hemorrhage and veriform streaks of the fundus in young dogs. Entropion Folliculitis and pedal furunculosis, bacterial Heterochromia iridis Hyperadrenocorticism Hypoplasia (or aplasia) of optic nerve Hypothyroidism Idiopathic epilepsy Idiopathic onychodystrophy Intervertebral disc diseasePredisposition due to breed conformation and other factors. Juvenile cellulitis Keratoconjunctivitis siccaDecreased tear production. Can progress to increased corneal vascularization and pigmentation. Linear IgA dermatosis Malasezia dermatitis Microphthalmia Mitral valve prolapse Nodular panniculitis (sterile) Pattern alopecia (ears) Pattern alopecia (ventral) Pemphigus foliaceous OsteopetrosisClinically similar to "swimmer" pups Radiographically uniformly dense bones and abnormal bone resorption. Over and undershot jaw in the Longhaired variety.Abnormal relative growth of the mandible and/or maxilla. PanniculitisInflammatory condition of the subcutaneous fat. Patent ductus arteriosus Pattern baldnessMales have bilateral alopecia of the ear pinnae Females have alopecia of the ventral body. Pemphigus foliaceous Persistent pupillary membrane Progressive Retinal Atrophy Progressive retinal degeneration (standard and miniatures) Renal hypoplasia Sensory neuropathy (longhairs) Sick sinus syndrome Sterile pyogranuloma syndrome Sternal callus Ureodermatologic syndrome Ununited anconeal process Vasculitis (idiopathic)
Dilated cardiomyopathy Mitral valve dysplasia
Acral furunculosis, bacterial Acral lick dermatitis Atrial septal defect
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E
Atopy Chemodectoma +/- pericardial effusion Cleft palate Constipation Demodicosis Facial fold intertrigo Fecal incontinance Folliculitis and pedal furunculosis, bacterial Follicular dysplasia (flank) Hypothyroidism Malassezia dermatitis Mitral vlave dysplacia Muzzle furunculosis, bacterial Perisstant right aortic arch Pulmonic stenosis Sterile pyogranuloma syndrome Subaortic stenosis Tail fold intertrigo Tetralogy fo Fallot Vascular compression of the esophagus Ventricular septal defect
Deafness Osteochondrosis of the spineAnterio-posterior herniation of the intervertebral end plate into the vertebral body stiff gait prevents proper galloping Occurs from 7-10 months of age.
Anaphylactic reaction to routine immunization Carcinoma and lymphosarcoma of oral and nasal cavity Cataract Craniomandibular osteoarthropathy Deafness Eclampsia Ectropion Entropion Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hip dysplasiaDeformed coxofemoral joints with clinical signs of none to severe hip lameness Radiographically there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease. HypoglycemiaConcentration of glucose in the blood below the normal limit. Progressive retinal atrophy Prolonged anesthesia Pyoderma Recessive juvenile amaurotic idiocyDullness and reduced vision at around 12-15 months of age. Developing into muscle spasms at 18 months, becoming seizures.
Central progressive retinal atrophyMottling and increased reflectivity of area centralis Resulting in loss of central vision Affecting dogs 3-5 years of age Difficulty in seeing stationary objects Sight is best in dim light. Cleft palateMedian fissures due to nonclosure of bones Environmental and/or genetic factors may be involved. Congenital Femoral Shift Congenital seborrhea Cutaneous asthenia (Ehlers-Danlos Syndrome)Connective tissue abnormality Fragile, lax skin Hyperextensibility of joints Diabetes mellitusInability to oxidize carbohydrates due to faulty pancreatic activity Results in hyperglycemia Symptoms of thirst, hunger, emaciation and weakness Dilated cardiomyopathy DistichiasisAn abnormal row of eyelashes Ectropion Entropion Epilepsy Episodic collapse Factor XI (PTA) deficiency Food hypersensitivity Fucosidosis Glaucoma Hanging tongue Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severe hip lameness Radiographically there may be shallow acetabulum, flattened femoral head, subluxation and secondary degenerative joint disease Hypothyroidism Idiopathic onychodystrophy Lip fold intertrigo Malasezia dermatitis Myasthenia gravis Otitis externa Patent ductus arteriosus Patellar luxationMedial/lateral Most common are medial Tibial rotation on the long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age Persistent atrial standstill Phosphofructokinase deficiencyEnzyme deficiency Diseased red blood cells and muscle cells Intermittent dark urine after strenuous exercise Persistent pupillary membrane Primary retinal dystrophy Progressive retinal degeneration type II Psoriasiform-lichenoid dermatosis Retinal dysplasia Seborrhea, primary Umbilical hernia Ventricular septal defect
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F
Anesthetic sensitivity Hip dysplasia Hypothyroidism Pyometra
Adult onset epilepsy Cleft palate Ectasia Luxated patella Pemphigus foliaceous
Diabetes insipidus Epilepsy Glaucoma Hip dysplasia Histiosarcoma Luxating patella Megaesophagus
Ataxia Atopic dermatitis Cataract Circumanal neoplasia Colonic disease Corneal dystrophyBoth epithelial(superficial) and endothelial(seen in Wire-haired Terriers) Deafness Degenerative valve disease Dislocation of the shoulder Distichiasis Ectopic ureter (familial relationship) Esophageal achalasia Glaucoma Goiter Juvenile cataract Legg-Perthes disease Lens luxation Persistent aortic archDevelopment from right aortic arch instead of left Crosses the esophagus forming a ring with the pulmonary artery and the ligamentum arteriosum Produces esophageal stenosis Pulmonic stenosisNarrow pulmonary artery at its origin Recessive oligodontia Secondary glaucoma Superficial corneal erosion (seen in Wire-haired Terriers) Tetralogy of Fallot (Wirehaired) Trichiasis (in Toy)
Brachury Cleft palate and lipMedian fissures due to non-closure of bones Elongated soft palate HemivertebraAsymmetric abnormal development of vertebrae which may result in neonatal death or cord compression in older puppies Affected vertebrae become wedge-shaped due to underdevelopment of one half Results in scoliosis or kinked tails and crowding of ribs if present in the thoracic area HemophiliaA, Factor VIII, or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hemophilia B, Factor IX deficiencyProlonged bleeding Abnormal prothrombin consumption and thromboplastin generation Decreased factor IX Heterozygotes with hemophilia B bleed more than heterozygotes with hemophilia A
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G
Atopic dermatitis Axonopathy Bacterial overgrowth (GI tract) Behavioral abnormalities Bilateral cataract Calcinosis circumscripta tongue CellulitisFolliculitis and furunculosis, bacterial Cleft of lip and palateMedial fissures due to nonclosure of bones Environmental and/or genetic factors may be involved. Collagen disorder of footpads Conjunctival dermoid cyst Contact hypersensitivity CystinuriaExcess cystine in the urine Predisposing to calculi. Deafness Dilated cardiomyopathy Discoid lupus erythematosus Ectasia syndrome Elbow dysplasia Enostenosis (Eosinophilic panostitis)Limb pain and intermittent lameness between the ages of 6 and 12 months Signs are persistent for two months Subsequent recovery. EpilepsyEEG may detect at an early age Esophageal achalasia Exocrine pancreatic insufficiency Eversion of nictitating membrane Fibrous subaortic stenosisNarrow aorta below its valve Flea bite hypersensitivity Fly dermatitis of ear tips Food hypersensitivity Gastroenteritis Hemophilia A, Factor VIII, or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT, reduced AHF and Factor VIII Hepatic angiosarcoma Hip dysplasiaDeformed coxofemoral joint Clinical signs ranging from none to severe hip lameness Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation and/or secondary degenerative joint disease. Hypothyroidism Infective endocarditis Inflammation of the third eyelid Inflammatory bowel disease INherited ventricular arrhythmias Insect or arachnid-related eosinophilic furunculosis (face) Lupoid onychodystrophy Megaesophagus Mitral valve dysplasia Mucocutaneous bacterial pyoderma Nasal furunculosis, bacterial Nodular dermatofibrosis with renal cystadenocarcinoma Oropharyngeal neoplasia Osteochondritis dissecans Osteosarcoma Otitis externa Palpebral dermoid Pancreatic insufficiency Pannus Patent ductus arteriosus Pemphigus erythematosus Perianal fistula Persistent right aortic archAortic development from right fourth aortic arch instead of left crosses the esophagus forming a ring around it with the pulmonary artery and the ligamentum arteriosum. Produces esophageal stenosis. Phimosis Pituitary dwarfism Progressive posterior paralysisOccurs in middle age to older dogs Some predilection for males Gradual onset Asymmetric in rear limbs Pyotraumatic dermatitis Renal cortical hypoplasia Right atrial hemangiosarcoma +/- pericardial effusion Seborrhea, primary Senile cataract Sialocele Silica uroliths Stress induced diarrhea Subaortic stenosis Systemic lupus erythematosus Tarsal fistulae Tricuspid vlave dysplasia Uberreiter's syndromeDegenerative pannus Chronic superficial keratitis Uterine leiomyomas Vascular anomaly with compression of the esophagus Vitiligo Von Willebrand's disease; pseodohemophilia; vascular hemophiliaProlonged bleeding time. Low factor VIII Reduced platelet adhesiveness and abnormal prothrombin consumption time. May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma subcutaneous hematomas
Amaurotic idiocyCNS storage disease Characterized at 6 months of age by nervousness and decreased training ability At 9-12 months progressive ataxia and impaired vision Corneal dystrophy Entropion Eversion of nictating membrane Fibrosarcoma LymphedemaNonpainful pitting edema Most commonly seen in the hind legs and in severe cases the entire body. Moderately affected animals gradually lose edema by 3 months of age Popliteal lymph nodes are absent or hypoplastic Malocclusion Melanoma Oropharyngeal neoplasia Pseudohermaphroditism Strabismus Subaortic stenosis Thrombocytopathy, platelet function defectModerate to severe bleeding diathesis Glanzmann's disease Subaortic stenosisNarrow aorta below its valve
Malocclusion Subcutaneous cysts
High incidence of hip dysplasia Hypothyroidism Malabsorption of cobalmin Osteochondritis dissecans Seborrhea Von Willebrand's disease
Acute moist dermatitis Acral lick dermatitis Atopy Bilateral cataract Canine X-linked muscular dystrophy Cataract with microphthalmiaOpaque lenses with small eyes Associated with retinal folds Central progressive retinal atrophyMottling and increased reflectivity of area centralis Resulting in loss of central vision. Difficulty in seeing stationary objects Sight is best in dim light Affecting dogs 3-5 years of age Central retinal degeneration Cerebellar hypoplasia Diaphragmatic hernia DistichiasisAn abnormal row of lashes Elbow dysplasia Elbow osteochondrosis Entropion Folliculitis and furunculosis, bacterial Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT, reduced AHF and Factor VIII Hip dysplasia Hypothyroidism Inhalant allergies Juvenile cellulitis Mitral vlave dysplasia Muscular dystrophy Nasal hypopigmentation Oropharyngeal neoplasia Osteosarcoma Pericardial effusion - idiopathic Pyotraumatic dermatitis Pyotraumatic folliculitis and furunculosis, bacterial Retinal dysplasia Right atrial hemangiosarcoma +/- pericardial effusion Sterile pyogranuloma syndrome Subvalvular aortic stenosis Taurine deficient familial Dilated cardiomyopathy Tricuspid valve dysplasia Von Willebrand's disease; pseudohemophilia; vascular hemophiliaProlonged bleeding time Low Factor VIII Reduced platelet adhesiveness and abnormal prothrombin consumption time. May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas
Atopy Cerebellar cortical abiotrophy Entropion Generalized progressive retinal atrophyAttenuation of retinal vessels Increased reflectivity of tapetum lucidum Affecting young dogs Characterized initially by night blindness Progressing to blindness Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severe hip lameness. Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and secondary degenerative joint disease. Hypothyroidism Juvenile cellulitis Progressive retinal degeneration
Acral furunculosis, bacterial Acral lick dermatitis Atopy Cervical calcinosis circumscripta Cerebellar hypoplasia CystinuriaExcess cystine in the urine Predisposing to calculi. DeafnessSeen in homozygous merles in conjunction with ocular defects. Dilated Cardiomyopathy -- x linked Elbow dysplasia Eversion of the nictitating membrane Folliculitis and furunculosis, bacterial Gastric dilitation-volvulus Heterochromia iridis"Walleye" Blue and white iris Hypothyroidism Lone atrial fibrillation Megaesophagus Metabolic bone disease MicrophthalmiaSmall eyes Result of merle to merle mating Seen in homozygous merles Mitral valve dysplasia Muzzle furunculosis, bacterial Necrotizing myelopathyAcute atraumatic, flaccid paralysis of the front limbs Osteochondritis dissecansSaucer shaped necrosis or flap in the posterior central portion of humeral head Causes very distinct favoring of affected limb Osteosarcoma Pedal furunculosis, bacterial Persistant right aortic arch Progressive ataxia Pulmonic stenosis Retinal dysplasia (Harlequin) Solar dermatosis (Harlequin) Spondylolisthesis"Wobbler syndrome" Anterior ventral canal is narrower than the posterior canal in the dorsoventral direction between C3 and C7 Stockard's paralysisPreganglionic sympathetic degeneration Onset at about 3 months of age Subaortic stenosis Tricuspid valve dysplasia
Achondroplasia Anophthalmia Blue eyes Brittle bone syndrome Cataracts Cleft palate Cryptorchidism Deafness Defective heart Demodicosis Entropion Factor IX(PTA) deficiency Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severs hip lameness Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease Malocclusion Missing dewclaws Monorchidism Persistent hyaloid artery Pyotraumatic dermatitis Slipped patella Tricuspid valve dysplasia
Anesthetic risk Azoturia-like diseaseExcessive nitrogen compounds in the urine Bloat Cheyletiellosis Esophageal achalasia Hemophilia A, Factor VII or AHF deficiencyHemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Lens luxation Megaesophagus Persistent pupillary membrane Persistent right aortic arch Predisposition to dystociaAnatomical peculiarities Fetal death Over nervousness of the dam Retinal dystrophy Short spine Von Willebrand's disease
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H
Hip dysplasia Malocclusion
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I
Allergic reaction to several chemicals Anesthesia risk Bloat Deafness Seizures Unilateral cryptorchidism
Acral furunculosis, bacterial Acral lick dermatitis Atopy Carpal luxation Cataract , juvenile cataract Color dilution alopecia Constipation Corneal dystrophy Deformed tail Dilated cardiomyopathy Distichiasis Enlarged orbit Entropion Fecal incontinence Folliculitis and furunculosis, bacterial Generalized myopathyStiff gait Swallowing difficulty Enlarged tongue Atrophic muscles First seen at 8 weeks of age Serum Creatine phosphokinase and aldolase levels are high Generalized progressive retinal atrophyAttenuation of retinal vessels Increased reflectivity of tapetum lucidum Affecting young dogs Characterized initially by night blindness and progressing to blindness GranulocytopathyIncreased susceptibility to infection Fever gingivitis Destruction of bone in mandibles, radius and ulna Hemophilia A,Factor VIII deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced Factor VIII Hip dysplasia Hypothyroidism Idiopathic epilepsy Inhalant allergies Megaesophagus Metabolic bone disease Osteochondritis dissecansInflammation, both bone and cartilage Results in splitting of cartilage into the joint Especially the knee and shoulder Osteosarcoma Persistent right aortic archAortic development from right fourth aortic arch instead of left and crosses the esophagus Forms a ring around the arch with the pulmonary artery and the ligamentum arteriosum Produces esophageal stenosis Persistent pupillary membrane Primary megaesophagus Progressive retinal degeneration type I (rod-cone dysplasia) Quadriplegia with amblyopiaProgressive Initially as swimmers at 3 days of age Later inability to stand and dim vision May be accompanied by tremor and nystagmus Right atrial hemangiosarcoma +/- pericardial effusion Seborrhea, primary Uredecrinatological syndrome Vascular anomaly with compression of the esophagus Wheat-sensitive enteropathy
CystinuriaExcess cystine in the urine Predisposing to calculi Hereditary footpad keratosis Hereditary myopathy Muscular dystrophy Tubular transport dysfunction
Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severe hip lameness Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease. Hypotrichosis Idiopathic onychodystrophy Malocclusion
Cataracts Dilated Cartiomyopathy Heart disease Hip and elbow dysplasia Hygroma of elbow Intrahepatic portosystemic shunts Lone atrial fibrillation Osteosarcoma Progressive retinal atrophy Rhinitis syndromeInflammation of mucous membrane of the nose Tail injury
Epilepsy Increased anesthetic risk Progressive Retinal Atrophy Patellar Luxation Vitreous Degeneration von Willebrand's disease Immune mediated thrombocytopenia Monorchidism Persistent right aortic archAortic development from right fourth aortic arch instead of left. Crosses the esophagus, forming a ring around it with the pulmonary artery and the ligamentum arteriosum. Produces esophageal stenosis.
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J
Deafness Demodicosis DermatophytosisTrichophyton mentagrophytes, var. erimacei Hereditary ataxia Legg perthes Luxating patella Salivary gland necrosis
Achondroplasia Monorchidism Return to Index.
K
Aberrant cilia Conotrunctal Defects (CTD) A series of genetically relaed congenital cardiac malformations that include conal septum, conal Ventricular septal defect, Tetralogy of Fallot, and persistant truncus arteriosus Ectopic cilia EpilepsyUsually seen at 3 years of age EEG may detect at an earlier age Hypogonadism of intact male Hyposomatotropism HypothyroidismDeficient thyroid activity Mitral valvedysplasia Patent ductus arteriosus Predisposition of melanoma Primary hyperparathyroidism Pulmonic stenosis Renal cortical hypoplasia Sebaceous cyst Tetralogy of FallotVentricular septal defect Pulmonary stenosis Dextroposition of the aorta Right ventricular hypertrophy
Cerebellar cortical and extrapyramidal nuclear abiotrophyOnset 9-16 weeks Pelvic limb stiffness Mild head tremor Progressing to paralysis Distichiasis Entropion Footpad keratoses (corns) Hair follicle tumors Keratoconjunctivitis sicca Narrow palpebral fissure Otitis externa Patent ductus arteriosus Spiculosis Trichiasis (upper lateral cilia) Ununited anconeal process
Cysts Entropion Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severe hip lameness Radiographically, there may be shallow acetabulum, flattened femoral head subluxation and secondary degenerative joint disease. Skin problems
Deafness Hip dysplasiaDeformed coxofemoral joints Clinical sighs from none to severe hip lameness Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation and secondary joint disease Return to Index.
L
Acral furunculosis, bacterial Acral lick dermatitis Associated occular and skeletal dysplasia AtherosclerosisLethargy Anorexia Welkness Collapse Vomiting Atopy Bilateral Cataract Canine congenital hypotrichosis Carpal subluxation (XR)Bilateral Gene is allelic to the gene for Hemophilia A Central progressive retinal atrophy (autosomal recessive)Screening available using the Optigen DNA marker testwww.optigen.com Mottling and increased reflectvity of area centralis resulting in loss of central vision Difficulty in seeing stationary objects Sight is best in dim light Affecting dogs 3-5 years of age. Central retinal degeneration Chronic hepatitis Coloboma Congenital phimosis and cutaneous mast cell tumors Copper toxicosis Corneal opacity Cortical degeneration Craniomandibular osteopathyIrregular osseous proliferation of mandible and tympanic bulla Discomfort from eating Intermittent fever up to 104 deg. F Beginning at age 4-7 months. Cystinuria (SLR)Excess cystine in the urine Predisposing to calculi Dacrocystitis Deficiency of type II muscle fibersSigns include a marked creatinuria and deficiency of muscle mass. Diabetes mellitisInability to oxideze carbohydrates due to faulty pancreatic activity Results in hypoglycemia with symptoms of thirst, hunger, emaciation, and weakness. Dilated cardiomyopathy DistichiasisAbnormal row of eyelashes Results in irritation and epiphora Dwarfism associated with retinal dysplasia Elbow osteochrondrosis Entropion Epilepsy Factor IX deficiency (congenital)Subcutaneous hematomas Profuse hemorrhage from surgical wound. Folliculitis and furunculosis, bacterial Food allergy Hemophilia A, Factor VIII or AHF deficiency (SLR)Prolonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hereditary myopathy Hip DysplasiaDeformed coxofemoral joints Clinical sighs from none to hip lameness Radiographically there may be shallow acetabulum, flattened femoral head, subluxation, and secondary degenerative joint disease. Hypertrophic osteodystrophy Hypoglycemiaconcentration of glucose in the blood below the normal limit. HypothyroidismDeficient thyroid activity Juvenile Cataract Leukotrichia Liver disease and liver cirrhosis (hereditary factors) Megaesophagus Melanoma Missing teeth Muscular dystrophyGeneralized muscle atrophy Depressed spinal reflexes "Bunny hopping" gait Nyatagmus Patent ductus arteriosus Pericardial effusion - idiopathic Persistent hyaloid artery Persistent pupillary membrane Postnatal cerebellar Prolapsed rectum Prolapsed uterus Pulmonic stenosis Pyotraumatic dermatitis Receptor dystrophy Retinal detachment Retinal dysplasia Right atrial hemangiosarcoma +/- pericardial effusion Sebborhea, primary Shoulder dysplasia Shoulder lameness Tricuspid valve disease Ununited anconeal process Waterline disease
Cryptorchidism DistichiasisAbnormal row of eyelashes Results in irritation and epiphora Lens luxation Undershot jawAbnormal relative growth of the mandible Ununited anconeal process Ventricular septal defect
Aberrant cilia Atopy Congenital hypotrichosis Corneal ulcers Degenerataive valve disease DistichiasisAbnormal row of eyelashes Results in irritation and epiphora Ectopic cilia Entropion (medial) Hip dysplasia Inguinal herniaFound in this breed to be high risk. Defective formation of linea alba associated with protrusion of abdominal contents through inguinal canal. Inhalant allergies Injection reaction Keratoconjunctivitis sicca Lack of ADH LissencephalyCongenital absence of cerebrocortical convolutions Signs within the first year of life Behavioral, visual and convulsive disorders. Malassezia dermatitis Patellar luxationMedial or lateral Most common are medial Accompanied by tibial rotation on the long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age. Progressive retinal atrophy Renal cortical hupoplasiaProven in this breed to be inherited Bilateral renal cortical hypoplasia leading to uremia and secondary hyperparathyroidism Signs begin at around 1 year of age
Protein-losing enteropathy Return to Index.
M
Aberrant cilia Blindness (congenital) Cryptorchidism Deafness Hypertrophic pyloric gastropathy Hydrocephalus HypoglycemiaConcentration of glucose in the blood below normal limit. Malocclusion of misalignment Patent ductus arteriosus Patellar luxationMedial or lateral Most common are medial Accompanied by tibial rotation on the long axis Bending of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age Poor pigmentation
Cutaneous asthenia Grand mal epilepsy Hypertrophic pyloric gastropathy Legg-Perthes diseaseAvascular necrosis of femoral head Secondary glaucoma; luxating lens
Bloat Ectropion Elbow dyslasia Mitral valve dysplasia Persistent pupillary membranes Pulmonic stenosis Vaginal hyperplasia
Corneal dystrophy Degenerative valve disease Dislocation of the shoulder Entropion Inguinal herniaDefective formation of linea alba associated with protrusion of abdominal contents through the inguinal canal. Keratoconjunctivitis sicca Legg-Perthes diseaseAvascular necrosis of femoral head Progressive retinal atrophyDilated pupils react sluggishly to stimuli Night blindness progrressing to blindness Atrophy of retinal vessels Increased reflectivity to tapetum lucidum Skin disease- lack of pigment
Atherosclerosis Atopy Atresia of lacrimal drainage apparatus Aurotrichia Bilateral cataract Corneal dystrophy Cryptorchidism Degenerative valve disease Distichiasis Esophageal achalasia Food allergy Hemorrhagic gastroenteritis Hyperlipidemia Hypothyroidism Inhalant allergy Juvenile cataract Juvenile renal disease Legg-Perthes diseaseAvascular necrosis of femoral head. Megaesophagus Microphthalmia Muscular dystrophy Nephritis Pancreatitis Patent ductus arteriosus Persistent pupillary membrane Portosystemic shunts Progressive retinal atrophy Prone to cystitis and bladder stones Pseudohermaphroditism Pulmonic stenosisNarrow pulmonary artery at its origin Schnauzer comedo syndromeComedo - from acranial to tail head Sertoli cell tumor Sick sinus syndrome Sinoatrial syncope Spinaliomas Subcorneal pustular dermatosis Von Willebrand's disease"Pseudohemophilia" "Vascular hemophilia" Incomplete autosomal dominant Prolonged bleeding time Low Factor VIII Reduced platelet adhesiveness and abnormal prothrombin consumption time May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas Return to Index.
N
Atrial septal defect Avulsion fractures Bloat Dilated Cardiomyopathy Dermoid cyst of the cornea Dilated cardiomyopathy Ectopic ureter Ectropion Elbow dysplasia Entropion Eversion of cartilage of the third eyelid. Folliculitis and furunculosis, bacterial Hip dysplasia Hot spots Kinked tails Megaesophagus Mitral valve dysplasia Mitral valve stenosis Patent ductus arteriosusPersistence and nonclosure of ductus arteriosus between aorta and pulmonary artery with right to left shunt Pemphigus foliaceus Pulmonic stenosis Pyotraumatic dermatitis Subvalvular aortic stenosisNarrow aorta below its valve Ununited anconeal process Ventricular septal defect
Cataracts Distichiasis Generalized progressive retinal atrophyAttenuation of retinal vessels Increased reflectivity of tapetum lucidum Affecting young dogs Characterized initially by night blindness Leading to blindness Glaucoma (Primary open-angle glaucoma) Keratoacanthoma Progressive retinal degeneration type I (rod dysplasia) Renal Cortical hypoplasiaProven in this breed to be inherited Bilateral renal cortical hypoplasia Leading to uremia Secondary hyperparathyroidism Signs begin at around 1 year of age Seborrhea Subcutaneous cysts
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O
Atopy Bilateral cataract Bloat Cataract (congenital) Demodicosis Dilated cardiomyopathy Distichiasis Elongated tongue Entropion Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to severe lameness. Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation , and/or degenerative joint disease. Immune mediated hemolytic anemia Juvenile cataracts Metachondrial myopathy Pedal furunculosis, bacterial Persistent atrial standstill Progressive retinal degeneration Retinal detachment Tricuspid valve disease Wobbler's syndromeSpondylolisthesis Anterior ventral canal is narrower than the posterior canal in the dorsal-ventral direction between C3 and C7.
Elbow dysplasia Hip dysplasia (severe)Deformed coxofemoral joints with clinical signs from none to severe hip lameness. Radiographically, there may be shallow acetabulum, flattened femoral head, subluxation, and/or secondary degenerative joint disease. Platelet disorder"Thrombocytopathy with giant platelets" Mild to moderately severe bleeding Prolonged bleeding time Abnormal platelet aggregation and adhesiveness Poor clot retraction Sebaceous cysts Return to Index.
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Anasarca Deafness Entropion Patellar luxationMedial or lateral, most common are medial Tibial rotation on the long axis Bending of the distal end and shallow femoral trochlea Lameness at 4-6 months of age
Atypical pannus Cheyletiellosis Corneal ulceration Cryptorchidism Degenerative valve disease DistichiasisTwo rows of eyelashes Results in irritation and epiphora Dystocia Ectopic cilia Elongated soft palate Hairy caruncle Hypoplasia of dens (Odontoid process)Either hypoplasia of dens or its nonunion with C2 produces atlantoaxial subluxation Onset any age Producing signs ranging from neck pain to quadriplegia Inguinal herniaDefective formation of linea alba associated with protrusion of abdominal contents through inguinal canal. Intervertebral disc diseasePredisposition possibly due to breed conformation and other factors Juvenile cataract Lacrimal duct atresiaCongenital absence of openings to lacrimal canal MicrophthalmiaAbnormal smallness of eyes More prone to urolith formation Nasal fold trichiasis Persistent penile frenulum Pigmentary keratitis Progressive retinal atrophyDilated pupils react sluggishly to stimuli Night blindness progressing to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum "Swimmers"Characterized by inability to stand at 4-6 weeks and flattened chest. TrichiasisIngrown eyelashes which irritate corneal conjunctiva Umbilical hernia
Cervical disc disease Cutaneous asthenia Ehlers-Danlos syndrome Connective tissue abnormality Fragile, lax skin and hyperextensibility of joints. CystinuriaExcess cystine in urine Predisposing to calculi Dermoid cyst Epilepsy Generalized progressive retinal atrophyAttenuation of retinal vessels Increased reflectivity of tapetum lucidum Affecting young dogs Characterized initially by night blindness Progressing to blindness. Hip dysplasia Von Willebrand's disease
Gastrointestinal disorders Aseptic Meningitis Autoimmune Disorders Cushing's Disease Elbow Dysplasia Hip Dysplasia Glaucoma Idiopathic Epilepsy Inguinal Hernias Luxating Patellas Malocclusion Patent Ductus Arteriosus Persistent Pupillary Membranes Retinal Dysplasia Thyroid Dysfunction (hypothyroidism most commonly seen) Umbilical Hernias Lymphocytic-plasmocytic gastritis Additional known conditions for this breed can be found on a list compiled by Dr. George Padgett at using the link below
Acral mutilation Bilateral cataract Bithoracic ectromeliaPresence of a scapula only with distal structures absent. Calcinosis circumscripta Callouses Cleft palate Colonic disease Deafness Demodicosis Epilepsy Entropion Eosinophilic Panostitis Esophageal sarcoma Follicular dysplasia (flank) Hepatic angiosarcoma Hereditary lupoid dermatosis Hip dysplasia Inherited dwarfism Neurotropic osteopathySigns at 3-9 months of age Characterized by toe gnawing Self mutilation low sensitivity in distal limbs Vascular degeneration Demyelination in spinal cord Progressive retinal degeneration Progressive retinal atrophyPupils react sluggishly Night blindness progressing to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum. Sensory neuropathy Umbilical hernia
Adrenal sex hormone abnormalities Atresia of lacrimal puncta Cryptorchidism Degenerative valve disease Dislocation of the shoulder Distichiasis Dwarfism and dystocia Elephant skin Epiphora Glycogen storage disease Hypersomatotropism Hypoplasia of dens (Odontoid process)Either hypoplasia of dens or its non-union with C2 produces atlantoaxial subluxation Onset at any age Producing signs from neck pain to quadriplegia Nasolacrimal puncta atresia Patella luxationMay be medial or lateral Most are medial Tibial rotation on its long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age Patent ductus arteriosusPersistence and nonclosure of ductus arteriosus between aorta and pulmonary artery with left to right shunt. Progressive retinal atrophyPupils react sluggishly Night blindness progressing to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum Open fontanelles Sick sinus syndrome Tracheal collapseDecreased rigidity Elongated elastic membrane and increased circumference of the tracheaa Occurs most commonly in obese dogs with dome-shaped heads, well-developed necks and narrow thoracic inlets Average age of 7 years May be surgically corrected Trichiasis
AchondroplasiaImpaired ossification of long bone cartilage Producing abnormal short limbs Adult onset Growth Hormone deficiency Amaurotic idiocy Atopic dermatitis Atresia of lacrimal puncta and nasolacrimal duct Atypical pannus Behavioral abnormalities Cerebrospinal demyelination Chronic superficial keratitis Cryptorchidism Congenital deafness Corneal dystrophy Corneal erosion, superficial Cushing's syndrome Cystinuria Degenerative valve disease Distichiasis Ear infections Ectodermal defectsSymmetrical areas of alopecia (Miniature Poodle) Affects 2/3 of body including head, ventral trunk, dorsal pelvic region and proximal legs. Ectopic ureters Entropion EpilepsyEEG may detect at an early age Epiphora Epiphyseal dysplasiaHindleg joints of puppies sag Puppies move with swaying gait of hindquarters Radiographically, "stippling" from defective ossification of epiphyseal site with several fine foci of bone. Glaucoma (primary narrow-angle) Hairlessness Heart valve incompetence HemeralopiaDay blindness Inability to see effectively in bright or direct light. Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hemorrhagic gastroenteritis Hypoplasia or aplasia of optic nerve Hyposomatotropism Hypospadia Hypothyroidism Injection reactions Intervetebral disc degeneration Iridal atrophy Juvenile cataracts Lacrimal duct atresia Legg-Perthes disease Lens-induced uveitis Microphthalmia Missing teeth Narcolepsy Neoplasia Nonspherocytic hemolytic anemia Optic nerve hypoplasia Osteogenesis Imperfecta Otitis externa Overly long hairs on the eyelid skin and cilia (upper lashes) Patent ductus arteriosus Patellar luxationMedial or lateral Most common are medial Tibial rotation on the long axis Bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age. Patent ductus arteriosus"Polygenic threshold trait" Persistence and nonclosure of ductus arteriosus between the aorta and pulmonary artery with left to right shunt. Persistent penile frenulum Progressive retinal atrophyPupils react sluggishly Night blindness progressing to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum. Progressive rod-cone degeneration Pseudohermaphroditism Pyruvate Kinase deficiency Renal dysplasia (genetic basis) Retinal atrophy Retinal detachment Robertsonian translocation Sialocele Superficial corneal erosion Ventricular septal defect Von Willebrand's diseaseProlonged bleeding time Low factor VII Reduced platelet adhesiveness Abnormal prothrombin consumption time May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas
Addison's Disease -- simple recessive Adult onset Growth hormone deficiency Alopecia (dilute colors) Atopic dermatitis Atrial septal defect Atypical pannus Behavioral abnormalities Bloat Cataract Distichiasis Entropion EpilepsyEEG may detect at an early age Epiphora Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding time Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hip dysplasia Hypothyroidism Iris atrophy Juvenile cataract Juvenile Renal disease -- recessive Lacrimal duct atresia Lobular dissecting hepatitis Malignant neoplasm Microphthalmia Osteogenesis imperfectaDeficient or delayed bone development Results in frequent fractures Appears at 6-8 weeks of age. Patent Ductus Arteriosus Progressive retinal atrophyPupils react sluggishly Night blindness progressing to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum Sebaceous adenitis Squamous cell carcinoma -- Black Standard Poodles Ventricular septal defect Von Willebrand's diseasePseudohemophilia vascular hemophilia Prolonged bleeding time Low Factor VII Reduced platelet adhesiveness and abnormal prothrombin consumption time May exhibit melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas
Addison's disease Cardiomyopathy Follicular dysplasia Gangliosidosis or G.M.I. Hip dysplasia INherited juvenile dilated cardiomyopathy Progressive retinal atrophy Puppy eye syndrome
Atopy Atrioventricular block Atypical pannus formation Cleft palate and lipsMedian fissures due to nonclosure of bones Environmental and/or genetic factors may be involved. Corneal dystrophy Delayed heat prostration Demodectic mange DistichiasisTwo rows of eyelashes Results in irritation and epiphora Elongated soft palate Encephalitis Entropion Hairy caruncle Hypotrichosis IntertrigoFacial fold Tail fold Due to wrinkled head Can become infectious Legg-Perthes diseaseAvascular necrosis of femoral head Male pseudohermaphroditismPresence of abdominal testicles, a vulva & an os penis Medial luxating patella Obesity Pigmentary keratitis Pinched nostril TrichiasisIngrown eyelashes which irritate corneal conjunctiva Urolithiasis
Deafness Hip dysplasiaDeformed coxofemoral joints Clinical signs from none to severe hip lameness Radiographically, there may be shallow acetabuluim, flattened femoral head, subluxation, and/or secondary joint disease. Temperament problems
Ectropion Entropion Persistant pupillary membrane Return to Index.
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Aggression Cervical vertebral deformity Congenital deafness Dermoid sinusTubular cyst in mid-dorsal line either anterior or posterior to the ridge Due to incomplete separation of skin and spinal cord during development from ectoderm Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to hip lameness Radiographically, there may be shallow acetabulum Flattened femoral head Subluxation Secondary degenerative joint disease HypothyroidismLumbosacral transitional vertebrae
Arthrosis of the elbow joint Congenital deafness Diabetes melitus Dilated cardiomyopathy Ectropion Elbow dysplasia Enlarged orbit Entropion Folliculitis and furunculosis, bacterial Gastric eosinophilis granuloma Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to severe hip lameness Radiographically there may be shallow acetabulum Flattened femoral head Secondary degenerative joint disease Idiopathic vasculitis Kidney failure (familial) Lack of traction at the lateral canthus Leukoencephalomalacia Muscular dystrophy Neuroaxonal dystrophy Osteochondrosis Oversized palpebral fissure Parvovirus Retinal dysplasia Subvalvular aortic stenosis VitiligoAsymptomatic depigmentation disease of the skin, mucosa and haircoat Return to Index.
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Acral lick granuloma Acromegaly Aphakia with multiple colobomasAbsence of lens associated with microphthalmia, acornea, retinal detachment, and anterior synechia Cardiomyopathy Deafness Dermoid cysts of corneaThick walled cyst containing sebaceous glands, hair follicles and sweat glands Diabetes mellitus Dilated cardiomyopathy DistichiasisTwo rows of eyelashes Resulting in irritation and epiphora Ectropion Elbow dysplasia Entropion Epilepsy Epithelial lined cysts of anterior pituitary Eversion of nictitating membrane Factor I deficiency, fibrinogen deficiency, afibrogenemia, hypo-fibrinogenemiaSevere or lethal hemorrhage Folliculitis and furunculosis, bacterial Gastric torsion Genu valgumKnees bowed medially due to rapid growth Prevalent in giant breeds Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hemophilia B , Factor IX deficiencyProlonged bleeding Abnormal prothrombin consumption and thromboplastin generation Reduced factor IX Heterozygotes with Hemophilia B bleed more than heterozygotes with Hemophilia A Hepato arteriovenous fistula Hip DysplasiaDeformed coxofemoral joints with clinical signs from none to severe hip lameness Radiographically there may be shallow acetabulum Flattened femoral head Subluxation Secondary degenerative joint diseas Hypertrophic osteopathy Hygroma Idiopathic degenerative joint disease Lip fold pyoderma Lymphoma Metabolic bone disease Osteochondrosis dissecans Osteosarcoma Oversized palpebral fissure Pyotraumatic dermatitis (hot spots) Redundant facial skin Retained cartilage of distal ulna Spleen torsion Stockard's paralysis Uveodermatologic syndrome
Black hair follicle dysplasia Glaucoma Persistent pupillary membrane Progressive retinal atrophy Progressive retinal degereration Retinal detachment Sensitive to barbiturates
Atrial septal defects Diabetes mellitus DwarfismRadiographic evidence of retarded growth apparent by 12 weeks of age Dysplasia of pectinate ligaments Glaucoma Growth hormone responsive dermatitis Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF and Factor VIII Hereditary nephritis Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to severe hip lameness Radiographically there may be shallow acetabulum Flattened femoral head Subluxation Degenerative joint disease Muscular dystrophy Persistent pupillary membrane Progressive retinal degeneration Pulmonic stenosis Retinal detachment Sebaceous cysts Subarotic stenosis Uveodermatological syndrome
Dermatitis Entropion Hay fever /asthma Hypothyroidism Legg-Perthes diseaseAvascular necrosis of the femoral head Narrow palpebral fissure Mucopolysaccharidosis Type IIIB -- Test available through the University of Pennsylvania Pemphigus foliaceous
Dilated Cartiomyopathy -- genetic basis not established Gastric torsion Osteochondrosis dissecans Osteosarcoma -- autosomal recessive Porto systemic liver shunt -- genetic basis not established Torsion of the lung Torsion of the spleen
AchondroplasiaImperfect ossification within the cartillage of long bones Producing dwarfism Alexander's disease Atopic dermatitis Bladder cancer Canine lymphoma Chronic hepatitis Craniomandibular osteopathy CystinuriaExcess cystine in the urind Predisposing to calculi Deafness Ear hematoma Elbow dysplasia Folliculitis and furunculosis, bacterial Hereditary nasal pyogranuloma and vasculitis Histiocytoma Intervertebral disc disease Luxation of the lens Melanoma Primary uterine inertia Pulmonic stenosis Pyogranulomatous and vasculitic disorder of nasal planum Pyometra Scottie crampRecessive Hyperkinetic disorder characterized by seemingly painless rigidity of limbs, back and tail muscle Both sexes are affected The head may be drawn between the front legs dog recovers in 15-30 seconds Oral Diazapam in doses of 0.5mg/kg given three times daily is highly effective in controlling episodes Splayleg Thyroid problem Urinary calculi Von Willebrand's disease, pseudohemophilia, vascular hemophiliaDominant Prolonged bleeding time Low Factor VII Reduced platelet adhesiveness Abnormal prothrombin consumption time May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas
Atopic dermatitis Atresia of the nasolacrimal duct Cataract Deafness Lens luxationResults in secondary glaucoma Retinal dysplasiaRecessive Jumbled, abnormally formed layers of the retina Retinal detachment Blindness Secondary glaucoma
Achondroplasia Bladder cancer Bilateral renal agenesis Cataract Central progressive retinal atrophyMottling and increased reflectivity of area centralis Results in lack of central vision Affects dogs starting at 3-5 years of age Difficulty in seeing stationary objects Sight best in dim light Choroidal hypoplasia Collie eye anomaly Coloboma Corneal dystrophy Deafness Degenerative valve disease Dermatomyositis Discoid lupus erythematosus Distichiasis Ectasia syndromeRecessive Excessive tortuosity of retinal vessels Choroio-retinal dysplasia Excavation of the optic disc Retinal detachment Intraocular hemorrhage Veriform streaks of the fundus in young dogs Ectopic cilia Epidermolysis bullosaOnset at 2-4 months of age Alopecia Erythema Scaling erosions Crusting Sometimes intact vesicle Familial dermatitis Folliculitis, bacterial Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF Reduced Factor VIII Heterochromia iridis"Walleye" Blue and white iris Hip dysplasiaPolygenic inheritance Deformed coxofemoral joints with clinical signs ranging from none to hip lameness Shallow acetabulum Flattened femoral head Subluxation Secondary degenerative joint disease Hypothyroidism Idiopathic ulcerative dermatosis Muscular dystrophy Nasal solar dermatitisHereditary susceptibility and lack of skin pigment predispose to the disease Patent ductus arteriosusPersistence and nonclosure of ductus arteriosus between the aorta and pulmonary artery Right to left shunt Personal Pupillary membrane Systemic lupus erythematosus Ulcer conditions of apocrine glands Uveodermatological syndrome Von Willebrand's disease Yeast dermatitis
Luxated patellas Reflex regurgitation Uveodermatological syndrome
Achondroplasia Atopy Chronic keratitis Clefts of lip and palateMedian fissures due to nonclosure of bones Environmental and/or genetic factors may be involved Corneal ulcers Degenerative valve disease Dermoids Entropion Hypospadia Hypertrophic pyloric gastrophy Inhalant allergies Progressive retinal atrophy Renal-cortical hypoplasiaBilateral renal cortical hypoplasia leading to uremia and secondary hyperparathyroidism Signs begin at about 1 year of age Renal dysplasia Retinal detachment Trichiasis Ventricular septal defect Vitriol syneresis Von Willebrand's diseaseProlonged bleeding time Low Factor VII Reduced platelet adhesiveness Abnormal prothrombin consumption time May exhibit recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma subcutaneous hematomas
Cataracts Congenital laryngeal paralysis Corneal dystrophy Discoid lupus erythematosus Distichiasis Ectopic ureter Eosinophilic granuloma Epilepsy Follicular dysplasia Hemophilia A Heterochromia iridis Hip dysplasia Hypogonadism in intact male Idiopathic onychodystrophy Lipidosis Oral eosinophilic granuloma Persistant pupillary membrane Progressive retinal atrophyDilated pupils react sluggishly Night blindness Progresses to blindness Atrophy of retinal vessels Increased reflectivity of tapetum lucidum Uveitis Ventricular septal defect Von Willebrand's disease, pseudohemophilia, vascular hemophiliaProlonged bleeding time Low Factor VII Reduced platelet adhesiveness Abnormal prothrombin consumption time Recurrent melena Prolonged estrual bleeding Excessive bleeding after trauma Subcutaneous hematomas Zinc responsive dermatosis
Color dilutant alopecia Congenital cardiovascular abnromalities Cryptorchidism Diabetes mellitus Hydrocephalus Legg-Perthes diseaseAvascular necrosis of the femoral head Occipital dysplasia Odontoid process dysplasia Patellar luxationMedial or lateral Most common are medial Tibial rotation on the long axis Bending at the distal end of the femoral shaft Shallow femoral trochlea lameness at 4-6 months Storage disease Tracheal collapse Yeast dermatitis
Allergies Autosomal thyroid disease Congenital kink tail Copper-associated hepatopathy Enlarged foramen magnum Hypoplasia of the larynx Juvenile limp Megaesophagus Premature closure of the distal radius Skye hepatitis Ulcerative colitis
Cataracts DermatitisSensitive to grass and fleas Heart disease Hereditary neuropathy Progressive retinal atrophy Renal dysplasia
Hip dysplasia Thyroid imbalance Vaginal prolapse
Bilateral cataract Clefts of lip and palateMedian fissures due to nonclosure of bones Environmental and/or genetic factors may be involved Juvenile cataract Primary vitreus
Atresia of nasolacrimal puncta Benign fatty tumors Cataract Conjunctivitis Follicular dermatitis Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF Reduced Factor VIII Hip dysplasia Hypothyroidism Narrow palpebral fissure Perianal adenomas Pulmonic stenosis
Heart murmurs / enlarged hearts Intervetebral disc disease
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lems luxationOxalate nephropathy Persistent pupillary membrane Progressive retinal atrophy
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Cataract Craniomandibular osteopathy Demodicosis Entropion Facial nerve paralysis Factor I defficiency Hemangiosarcoma Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF Reduced Factor VIII Hip Dysplasia Hyperpigmentation Idiopathic Epilepsy -- possibly autosomal recessive Lymphoma Osteochondritis Dissecans Osteochondrosis Progressive Retinal Atrophy Sebaceous adenitis Spinal Dysraphism Sterile Pyogranuloma Syndrome Syringomyelia Umbilical Hernia Vasculitis Return to Index.
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Bloat Cutaneous mast cell tumor Cryptorchidism Dermoid cyst of cornea Distichiasis Double eyelashes Dwarfism Enlarged your Entropion Eversion of nictitating membrane Fibrosarcoma Hemophilia A, Factor VIII or AHF deficiencyProlonged bleeding Hemorrhagic episodes Prolonged PTT Reduced AHF Reduced Factor VIII Hip dysplasia Hypertropic Osteodystrophy Myasthenia gravis Oropharyngeal neoplasia Peritoneopericardial diaphragmatic hernia Spinal dysraphismBegins at 4-6 weeks of age Not progressive Crouching stance Abduction of one leg Hopping gait Abnormal proprioception in hindlegs Sterile pyogranuloma syndrome Tricuspid valve disease Umbilical hernia Undershot jawAbnormal growth of mandible Ununited anconeal process
Central retinal atrophy Superficial corneal erosion Persistent pupillary membrane Progressive retinal degeneration Secondayr glaucoma
Hip dysplasia (infrequent) Hereditary cataract Hypothyroidism Primary glaucoma Spermatogenic arrest with azoospermia
Luxated lens / secondary glaucoma
Atopic dermatitis Cardiomyopathy Cataracts Chronic hepatitis Cirrhosis of the liver Cleft palates Copper-associated hepatopathy Craniomandibular osteopathyIrregular osseous proliferation of mandible and tympanic bulla Discomfort from eating Intermittent fever up to 104 deg F Begins at 4-7 months Progresses to 11-13 months then may stop Deafness Degenerative valve disease Ectopic ureter Epidermal dysplasia Enlarged orbit Fatty liver syndrome Globoid cell leukodystrophy (Krabbe's disease)Progressive signs beginning at 3-6 months old Pelvic stiffness Cerebellar disturbance CSF total protein elevated Enzyme deficiency with collections of globoid cells in the DNS Hip dysplasia Ichthyosis Inguinal hernia Defective formation of linea alba associated with protrusion of abdominal contents through inguinal canal Keratoconjunctivitis sicca Legg-Perthes diseaseAvascular aseptic necrosis of femoral head Luxating patella Malasezia dermatitis Myotonia Pulmonic stenosis Pyruvate kinase deficiency Seborrhea, primary Tetralogy of Fallot Ventricular septal defect
Cryptorchidism Degenerative valve disease Demodectic mangeCommunicable Due to demodex in hair follicles Idiopathic onychodystrophy Multiple Drug SensitivityOccurs in at least one line of Longhaired Whippets you can refer to the original article at: http://www.pnas.org/cgi/reprint/101/32/11725 MDR1 gene Problme drugs: Ivermectin, Loperamide, Doxorubicin, Vincristine, Vinblastine, Cyclosporin, Digoxin, Acepromazine, Butorphanol Potential Problem Drugs: Ondansetron, Domperidone, Paclitaxel, Mitoxantrone, Etoposide, Rifampicin, Quinidine, Morphine Test available:http://www.vetmed.wsu.edu/depts-VCPL/test.asp Partial alopeciaAffects 2/3 of body including head, trunk (ventral) , dorsal pelvic region and proximal legs
Color dilution alopecia Megaesophagus Tetralogy of fallot
Hip dysplasiaDeformed coxofemoral joints with clinical signs from none to hip lameness Shallow acetabulum Flattened femoral head Subluxation Secondary joint disease Return to Index.
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Color dilution alopecia Degenerative valve disease Dermatophytosis DistichiasisTwo rows of eyelashes Results in irritation and epiphora Fatty liver syndrome Hydrocephalus Hypoplasia of densEither hypoplasia of dens or its nonunion with C2 Produces atlantoaxial subluxation Onset about any age producing signs ranging from neck pain to quadriplegia Injection reactions Keratoconjunctivitis sicca Legg-Perthes disease Lymphangiectasia Melanoderma Patent ductus arteriosus Patellar luxationMedial or lateral Medial is more common Tibial rotation on its long axis bending of the distal end of the femoral shaft Shallow femoral trochlea Lameness at 4-6 months of age Portosystemic shunts Retinal dysplasia Tracheal alopecia Return to Index.
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Cardiology Listings based upon "Manual of Canine and Feline Cardiology" fourth edition 2008, W.B. Saunders
by Larry P. Tilley, Francis W.K. Smith, Jr., Mark A. Oyama, and Meg M Sleepe